GSM576637[Accession] - GEO DataSets

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Items: 3

Select item 2000235261.

Evolution combined with genomic study elucidates genetic bases of isobutanol tolerance in Escherichia coli

(Submitter supplied) BACKGROUND:Isobutanol is a promising next generation biofuel with demonstrated high yield microbial production, but the toxicity of this molecule reduces fermentation volumetric productivity and final titers. Organic solvent tolerance is a complex, multigenic phenotype that has been recalcitrant to rational engineering approaches. We apply experimental evolution followed by genome resequencing and a gene expression study to elucidate genetic bases on adaptation to exogenous isobutanol stress. more...

Organism:: Escherichia coli str. K-12 substr. MG1655; Escherichia coli

Type:: Expression profiling by array

Platform:: GPL10751
12 Samples

Download data: GPR

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Accession:: GSE23526

ID:: 200023526

Analyze with GEO2R

Select item 1000107512.

MYcroarray CUSTOM Ecoli-str:K12-substr:MG1655 80K-6rep v1.0

(Submitter supplied) Circular features are ~55um in diameter. 4,280 E. coli genes are surveyed. The number of unique probe sequences per gene is either three (n = 3723), two (n =352) or one (n = 205). Consequently, there are 12,078 unique probe sequences surveying E. coli genes on the array. All probe sequences are replicated 6 times, so there are 72,468 E. coli probes on the array. In addition, there are 1,440 proprietary QC probe sequences on the array, 224 are for assessing hybridization efficiency. more...