GSM5866813[Accession] - GEO DataSets

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Items: 4

Select item 2001962721.

Distinct N6-methyladenosine (m6A) Regulation of Innate Immune Responses During Bacterial and Viral Infections

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens; Mus musculus

Type:: Other

Platforms:: GPL11154 GPL13112 GPL21493
38 Samples

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Accession:: GSE196272

ID:: 200196272

PubMed Full text in PMC Similar studies

Select item 2001962702.

Distinct N6-methyladenosine (m6A) Regulation of Innate Immune Responses During Bacterial Infections II

(Submitter supplied) N6-methyladenosine (m6A) is a dynamic post-transcriptional RNA modification influencing all aspects of mRNA biology. Here, we examined cellular m6A epitranscriptomes during P.aeruginosa infection to identify m6A-regulated innate immune response genes with or without ALKBH5 knockdown. We showed that a significant portion of cellular genes including many innate immune response genes underwent m6A modifications in 5’UTR and 3’UTR, from which we identified common and distinct m6A-modified genes under different stimulating conditions.