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Items: 4

1.

Major functional transcriptome of an inferred center regulator of an ER(-) breast cancer model system

(Submitter supplied) We aimed to find clinically relevant gene activities ruled by the signal transducer and activator of transcription 3 (STAT3) proteins in an ER(-) breast cancer population via network approach. STAT3 is negatively associated with both lymph nodal category and stage. MYC is a component of STAT3 network. MYC and STAT3 may co-regulate gene expressions for Warburg effect, stem cell like phenotype, cell proliferation and angiogenesis. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL887
102 Samples
Download data: TXT
Series
Accession:
GSE32641
ID:
200032641
2.

The inferred mechanisms for prognostic features of signal transducer and activator of transcription 3 in an ER(+) breast cancer model system

(Submitter supplied) Abstract Aberrantly expressed signal transducer and activator of transcription 3 (STAT3) predicts poor prognosis primarily in estrogen receptor positive (ER(+)) breast cancers and activated STAT3 is overexpressed in luminal A subtype cells. The mechanisms contributing to the prognosis and/or subtype relevant features of *STAT3* in ER(+) breast cancers are* *through multiple interacting regulatory pathways including STAT3-MYC, STAT3-ER , STAT3-MYC-ER interactions and the direct action of activated STAT3. more...
Organism:
Homo sapiens
Type:
Expression profiling by array; Third-party reanalysis
Platform:
GPL887
119 Samples
Download data: TXT
Series
Accession:
GSE24124
ID:
200024124
3.

Agilent-012097 Human 1A Microarray (V2) G4110B (Feature Number version)

(Submitter supplied) Agilent's Human 1A Oligo Microarray (V2) includes over 20K 60-mer oligonucleotide probes, sourced from the Incyte Foundation Database, RefSeq, and GenBank, and are designed to span conserved exons across the transcripts of the targeted full length genes. Coupled with Agilent's probe selection and validation processes, this design method gives the customer maximum confidence in data quality and prevents redundancy in gene coverage. more...
Organism:
Homo sapiens
8 DataSets
98 Series
1 Related Platform
2172 Samples
Download data: TXT
Platform
Accession:
GPL887
ID:
100000887
4.

breast tumor part_IDC_rep1 5385

Organism:
Homo sapiens
Source name:
Infiltrating Ductal Carcinoma (IDC), Buffer 1, ER(-), PR(-). (channel 1) Commercially available. (channel 2)
Platform:
GPL887
Series:
GSE24124 GSE32641
Download data: TXT
Sample
Accession:
GSM593799
ID:
300593799
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