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Items: 3

1.

TREM2+ and interstitial macrophages orchestrate airway inflammation in SARS-CoV-2 infection in rhesus macaques

(Submitter supplied) The COVID-19 pandemic remains a global health crisis, yet, the immunopathological mechanisms driving the development of severe disease remain poorly defined. Here, we utilize a rhesus macaque (RM) model of SARS-CoV-2 infection to delineate perturbations in the innate immune system during acute infection using an integrated systems analysis. We found that SARS-CoV-2 initiated a rapid infiltration (two days post infection) of plasmacytoid dendritic cells into the lower airway, commensurate with IFNA production, natural killer cell activation, and induction of interferon-stimulated genes. more...
Organism:
Macaca mulatta
Type:
Expression profiling by high throughput sequencing
Platform:
GPL27943
101 Samples
Download data: TXT
Series
Accession:
GSE198882
ID:
200198882

PubMed Full text in PMC Similar studies

2.

Illumina NovaSeq 6000 (Macaca mulatta)

Organism:
Macaca mulatta
141 Series
13170 Samples
Download data
Platform
Accession:
GPL27943
ID:
100027943

3.

PBMCs, p20097-s030

Organism:
Macaca mulatta
Source name:
PBMC
Platform:
GPL27943
Series:
GSE198882
Download data
Sample
Accession:
GSM5958839
ID:
305958839

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db=gds|term=GSM5958839[Accession]|query=6|qty=2|blobid=MCID_6733ef7a3ec0a11b447f9d4c|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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