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Items: 3

1.

Transcriptomic analysis of homoserine-evolved MG1655 strain (wild type) and of homoserine -treated wild type, mutant deleted for thrL and mutant bearing thrL* allele

(Submitter supplied) The growth of E. coli is inhibited by millimolar concentrations of L-homoserine, which may be problematic for the industrial production of this compound or for products derived from it. In this work, an adapted laboratory evolution (ALE) was applied, which resulted in the isolation of an E. coli strain at least 10-fold more tolerant to L-homoserine than the original (MG1655) strain. Only four genomic modifications were identified after genome sequencing of this evolved strain (designed 4E), including a 49 bp truncation starting from the codon stop of thrL and leading to a modified thrL locus carrying a thrL* allele encoding a 30 amino acids polypeptide, which is 9 amino acids more than the leader peptide encoded by thrL. more...
Organism:
Escherichia coli str. K-12 substr. MG1655; Escherichia coli; Escherichia coli O157:H7 str. EDL933; Escherichia coli CFT073; Escherichia coli O157:H7 str. Sakai
Type:
Expression profiling by array
Platform:
GPL13359
24 Samples
Download data: TXT, XLSX
Series
Accession:
GSE206196
ID:
200206196

PubMed Full text in PMC Similar studies

2.

Agilent-020097 E. coli Gene Expression Microarray (Probe Name version)

(Submitter supplied) E. coli (K12-MG1655, CFT073, O157-H7 EDL933, O157-H7 VT2-Sakai) Oligo Microarray *** The ID column includes the Agilent Probe Names. A different version of this platform with the Agilent Feature Extraction feature numbers in the ID column is assigned accession number GPL13360. Protocol: see manufacturer's web site at http://www.agilent.com/
Organism:
Escherichia coli O157:H7 str. EDL933; Escherichia coli CFT073; Escherichia coli O157:H7 str. Sakai; Escherichia coli str. K-12 substr. MG1655
21 Series
1 Related Platform
203 Samples
Download data
Platform
Accession:
GPL13359
ID:
100013359

3.

thrL mutant grown in the presence of homoserine S1

Organism:
Escherichia coli
Source name:
thrL mutant grown in the presence of homoserine
Platform:
GPL13359
Series:
GSE206196
Download data: TXT
Sample
Accession:
GSM6245890
ID:
306245890

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db=gds|term=GSM6245890[Accession]|query=7|qty=6|blobid=MCID_66c9a300ba59ee397aa7309d|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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