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Items: 4

1.

C99R mutation in IRF4 drives a novel gain of function binding and gene upregulation in classical Hodgkin lymphoma [Illumina BeadChip]

(Submitter supplied) Disease-causing mutations in genes encoding transcription factors (TF) are frequent in hematopoietic malignancies and might affect TF-interactions with respective DNA-binding motifs. Here, we report the characterization of a recurrent somatic mutation c.295T>C in the IRF4 gene in classic Hodgkin lymphoma (cHL) leading to a C99R exchange. IRF4-C99R is located in the center of the IRF4 alpha3-recognition helix contacting the DNA 5´-GAAA-3´ IRF consensus sequence. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL10558
24 Samples
Download data: IDAT
Series
Accession:
GSE211913
ID:
200211913

PubMed Full text in PMC Similar studies Analyze with GEO2R

2.

C99R mutation in IRF4 drives a novel gain of function binding and gene upregulation in classical Hodgkin lymphoma

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by array
Platforms:
GPL11154 GPL13393 GPL10558
63 Samples
Download data: IDAT
Series
Accession:
GSE211445
ID:
200211445

PubMed Full text in PMC Similar studies Analyze with GEO2R

3.

Illumina HumanHT-12 V4.0 expression beadchip

(Submitter supplied) The HumanHT-12 v4 Expression BeadChip provides high throughput processing of 12 samples per BeadChip without the need for expensive, specialized automation. The BeadChip is designed to support flexible usage across a wide-spectrum of experiments. The updated content on the HumanHT-12 v4 Expression BeadChips provides more biologically meaningful results through genome-wide transcriptional coverage of well-characterized genes, gene candidates, and splice variants. more...
Organism:
Homo sapiens
51 DataSets
2937 Series
4 Related Platforms
104380 Samples
Download data: TXT
Platform
Accession:
GPL10558
ID:
100010558

4.

BJAB_IRF4WT_0hrs_rep1

Organism:
Homo sapiens
Source name:
0-hrs Dox Tet-inducible IRF4WT transfected BJAB cells
Platform:
GPL10558
Series:
GSE211445 GSE211913
Download data: IDAT
Sample
Accession:
GSM6505372
ID:
306505372

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