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Items: 4

1.

Zygotic genome activation by the totipotency pioneer factor Nr5a2 IV

(Submitter supplied) Life begins with a switch in genetic control from the maternal to the embryonic genome during zygotic genome activation (ZGA). Despite its importance, the essential regulators of ZGA remain largely unknown in mammals. Based on de novo motif searches, we identified the orphan nuclear receptor Nr5a2 as a key activator of major ZGA in mouse 2-cell embryos. Nr5a2 is required for progression beyond the 2-cell stage. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL19057
137 Samples
Download data: CSV
Series
Accession:
GSE213682
ID:
200213682
2.

Zygotic genome activation by the totipotency pioneer factor Nr5a2

(Submitter supplied) Life begins with a switch in genetic control from the maternal to the embryonic genome during zygotic genome activation (ZGA). Despite its importance, the essential regulators of ZGA remain largely unknown in mammals. Based on de novo motif searches, we identified the orphan nuclear receptor Nr5a2 as a key activator of major ZGA in mouse 2-cell embryos. Nr5a2 is required for progression beyond the 2-cell stage. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL19057
398 Samples
Download data
Series
Accession:
GSE178661
ID:
200178661
3.

Illumina NextSeq 500 (Mus musculus)

Platform
Accession:
GPL19057
ID:
100019057
4.

Single 2 cell embryo. Sample 3 ex1 Condition: SR1848_NR5A2OE

Organism:
Mus musculus
Source name:
single embryo
Platform:
GPL19057
Series:
GSE178661 GSE213682
Download data
Sample
Accession:
GSM6592005
ID:
306592005
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Supplemental Content

db=gds|term=GSM6592005[Accession]|query=1|qty=2|blobid=MCID_66dc7bc208e11e13478ac95a|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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