GSM6812362[Accession] - GEO DataSets

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Items: 4

Select item 2002207831.

Cannabinoid modulation of gene and microRNA expression in brain (basal ganglia) during chronic HIV/SIV infection

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Macaca mulatta; Homo sapiens

Type:: Expression profiling by high throughput sequencing; Expression profiling by RT-PCR

Platforms:: GPL17837 GPL27943
31 Samples

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Accession:: GSE220783

ID:: 200220783

Select item 2002207092.

MicroRNA profiling of Basal ganglia tissue from chronically SIV infected rhesus macaques II

(Submitter supplied) The study describes miRNA expression changes in basal ganglia (BG) of chronically SIV-infected rhesus macaques. HIV/SIV-associated neurological disorder (HAND) represents a major comorbidity affecting HIV patients on anti-retroviral therapy. Employing a systems biology approach, we report molecular changes underlying HAND and its modulation by phytocannabinoids [delta-9-tetrahydrocannabinol (9-THC)] in uninfected and SIV-infected rhesus macaques (RMs) treated with vehicle (VEH/SIV) or 9-THC (THC/SIV). more...