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Items: 4

1.

Loss of PPARα function promotes epigenetic dysregulation of lipid homeostasis driving ferroptosis and pyroptosis lipotoxicity in Metabolic Dysfunction Associated Steatotic Liver Disease (MASLD)

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus
Type:
Methylation profiling by genome tiling array; Expression profiling by high throughput sequencing
Platforms:
GPL32685 GPL24247
24 Samples
Download data: IDAT
Series
Accession:
GSE239279
ID:
200239279

PubMed Full text in PMC Similar studies Analyze with GEO2R

2.

Loss of PPARα function promotes epigenetic dysregulation of lipid homeostasis driving ferroptosis and pyroptosis lipotoxicity in Metabolic Dysfunction Associated Steatotic Liver Disease (MASLD) [RNA-seq]

(Submitter supplied) Metabolic Dysfunction Associated Steatotic Liver Disease (MASLD) is a growing epidemic with an estimated prevalence of 20‑30% in Europe and the most common cause of chronic liver disease worldwide. The onset and progression of MASLD are orchestrated by an interplay of the metabolic environment with genetic and epigenetic factors. Emerging evidence suggests altered DNA methylation pattern as a major determinant of MASLD pathogenesis coinciding with progressive DNA hypermethylation and gene silencing of the liver‑specific nuclear receptor PPARα, a key regulator of lipid metabolism. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24247
12 Samples
Download data: TSV
Series
Accession:
GSE238201
ID:
200238201

PubMed Full text in PMC Similar studies

3.

Illumina NovaSeq 6000 (Mus musculus)

Organism:
Mus musculus
14170 Series
692715 Samples
Download data
Platform
Accession:
GPL24247
ID:
100024247

4.

WT_CHOW_3

Organism:
Mus musculus
Source name:
liver
Platform:
GPL24247
Series:
GSE238201 GSE239279
Download data
Sample
Accession:
GSM7660273
ID:
307660273

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db=gds|term=GSM7660273[Accession]|query=26|qty=2|blobid=MCID_672913a391da88433d169734|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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