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Items: 4

1.

TET1 catalytic activity is required for reprogrammign of imprinting control regions and the patterning of sperm-specific hypomethylated regions [RNA-Seq]

(Submitter supplied) DNA methylation erasure is required for mammalian primordial germ cell reprogramming. TET enzymes iteratively oxidize 5-methylcytosine to generate 5-hyroxymethylcytosine (5hmC), 5-formylcytosine, and 5-carboxycytosine to facilitate active genome demethylation. Whether these bases are required to promote replication-coupled dilution or activate base excision repair during germline reprogramming remains unresolved due to the lack of genetic models that decouple TET1 activities. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL32159
13 Samples
Download data: TXT
Series
Accession:
GSE249772
ID:
200249772
2.

TET1 catalytic activity is required for reprogrammign of imprinting control regions and the patterning of sperm-specific hypomethylated regions

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus
Type:
Genome binding/occupancy profiling by high throughput sequencing; Methylation profiling by genome tiling array
Platforms:
GPL31950 GPL32159 GPL21103
63 Samples
Download data: BEDGRAPH, BW, CSV, IDAT, NARROWPEAK
Series
Accession:
GSE224459
ID:
200224459
3.

NextSeq 1000 (Mus musculus)

Platform
Accession:
GPL32159
ID:
100032159
4.

E14.5 Male PGC RNAseq Tet1-WT4

Organism:
Mus musculus
Source name:
WT PGC4
Platform:
GPL32159
Series:
GSE224459 GSE249772
Download data
Sample
Accession:
GSM7963978
ID:
307963978
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