GSM8024460[Accession] - GEO DataSets - NCBI

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Items: 4

Select item 2002536361.

TET1 catalytic activity is required for reprogrammign of imprinting control regions and the patterning of sperm-specific hypomethylated regions [RNA-seq: Female PGCs]

(Submitter supplied) DNA methylation erasure is required for mammalian primordial germ cell reprogramming. TET enzymes iteratively oxidize 5-methylcytosine to generate 5-hydroxymethylcytosine (5hmC), 5-formylcytosine, and 5-carboxycytosine to facilitate active genome demethylation. Whether these bases are required to promote relication coupled dilution or active base excision repair during germline reprogramming remains unresolved due to the lack of genetic models that decouple TET1 activities. more...

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing

Platform:: GPL32159
12 Samples

Download data: TXT

Series

Accession:: GSE253636

ID:: 200253636

Select item 2002244592.

TET1 catalytic activity is required for reprogrammign of imprinting control regions and the patterning of sperm-specific hypomethylated regions

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Genome binding/occupancy profiling by high throughput sequencing; Methylation profiling by genome tiling array

Platforms:: GPL31950 GPL32159 GPL21103
63 Samples

Download data: BEDGRAPH, BW, CSV, IDAT, NARROWPEAK

Series

Accession:: GSE224459

ID:: 200224459

PubMed Similar studies

Select item 1000321593.

NextSeq 1000 (Mus musculus)

Organism:: Mus musculus

39 Series
650 Samples

Platform

Accession:: GPL32159

ID:: 100032159

Select item 3080244604.

E14.5 Female PGC RNAseq Tet1-WT2

Organism:: Mus musculus

Source name:: Primordial germ cell

Platform:: GPL32159
Series:: GSE224459 GSE253636

Sample

Accession:: GSM8024460

ID:: 308024460

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GSM8024460[Accession] (4)
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