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Items: 4

1.

Basis of gene-specific transcription regulation by the Inegrator Complex (ChIP-Seq II)

(Submitter supplied) Integrator (INT) is a multi-subunit modular RNA processing complex, which exhibits both RNA endonuclease and protein phosphatase activity. It is responsible for transcription termination at the 3’ ends of a diverse array of RNA polymerase II (RNAP2) transcribed non-coding RNAs, as well as transcription regulation at a large number of protein coding genes. There, it terminates RNAP2 at promoter proximal pausing sites, cleaves the nascent transcript and competes with elongation factors.This INT-mediated tapering of gene expression attenuates stimulus responsive genes and is essential for cell differentiation. more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL34284 GPL24676
16 Samples
Download data: BED, BIGWIG
Series
Accession:
GSE260520
ID:
200260520
2.

Basis of gene-specific transcription regulation by the Inegrator Complex

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL34284 GPL24676
63 Samples
Download data: BED, BIGWIG
Series
Accession:
GSE233958
ID:
200233958
3.

Illumina NovaSeq X Plus (Homo sapiens)

Platform
Accession:
GPL34284
ID:
100034284
4.

INTS13 ChIP, HDGF depletion, HEK293T, Rep1

Organism:
Homo sapiens
Source name:
HEK293T
Platform:
GPL34284
Series:
GSE233958 GSE260520
Download data: BIGWIG
Sample
Accession:
GSM8118808
ID:
308118808

Supplemental Content

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