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Items: 4

1.

Correlation of antigen expression with epigenetic modifications after rAAV delivery of a human Factor IX variant in mice and rhesus macaques

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus; Macaca mulatta
Type:
Genome binding/occupancy profiling by high throughput sequencing; Other
4 related Platforms
64 Samples
Download data: BEDGRAPH
Series
Accession:
GSE261047
ID:
200261047
2.

Correlation of antigen expression with epigenetic modifications after rAAV delivery of a human Factor IX variant in mice and rhesus macaques (Tn5 NHP)

(Submitter supplied) We investigated long-term human coagulation Factor IX expression of a novel variant when delivered into mice and rhesus macaques and compare transduction efficiencies using two different AAV capsids. In hemophilic mice injected with KP1-packaged rAAV expressing the hyperactive FIX variant specific activity plasma levels were 10-fold or 2-fold enhanced when compared to wild-type or Padua huFIX injected mice, respectively. more...
Organism:
Macaca mulatta
Type:
Other
Platform:
GPL27943
6 Samples
Download data: BEDGRAPH
Series
Accession:
GSE261046
ID:
200261046
3.

Illumina NovaSeq 6000 (Macaca mulatta)

Organism:
Macaca mulatta
129 Series
11833 Samples
Download data
Platform
Accession:
GPL27943
ID:
100027943
4.

R1-NHP-57_KP1

Organism:
Macaca mulatta
Source name:
liver
Platform:
GPL27943
Series:
GSE261046 GSE261047
Download data: BEDGRAPH
Sample
Accession:
GSM8133096
ID:
308133096
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Supplemental Content

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