GEO DataSets

(Submitter supplied) The molecular basis linking folate deficiency to certain health conditions and developmental defects is complex and not fully understood. In this study, we examined the consequences of folate deficiency on global gene expression by microarray analysis and compared transcript levels in normal human fibroblast cells (GM03349) grown in folate deficient and sufficient medium. Keywords: folate depletion, stress response, comparative genomic hybridization

Organism:

Homo sapiens

Type:

Expression profiling by array

Platforms:

GPL3036 GPL3037

8 Samples

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(Submitter supplied) This array was developed in-house at NIEHS, and used for gene expression profiling experiments. A complete listing of the genes on this chip is available at the following Web site: http://dir.niehs.nih.gov/microarray/chips.htm Oligos for spotting were purchased from the Operon Human Genome Oligo Set V1.1 and cDNAs were prepared according to DeRisi et al., 1996, Nat. Genet. 14, 457-460. The PCR products from the cDNAs and the oligos were spotted onto poly-L-lysine-coated glass slides using a modified, robotic DNA arrayer (Beecher Instruments, Bethesda MD). more...

Organism:

Homo sapiens

1 Series

4 Samples

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