GSM8180309[Accession] - GEO DataSets

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Items: 4

Select item 2002628451.

Antitumor progenitor exhausted CD8 T cells are sustained with TCR engagement

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Methylation profiling by high throughput sequencing

Platform:: GPL24247
46 Samples

Download data: BW, MTX, TSV, TXT

Series

Accession:: GSE262845

ID:: 200262845

PubMed Similar studies

Select item 2002628432.

Antitumor progenitor exhausted CD8 T cells are sustained with TCR engagement [WGBS]

(Submitter supplied) Durability of an antitumor immune response is mediated in part by the persistence of progenitor exhausted CD8 T cells (Tpex). Tpex serve as a source for the pool of effector T cells, and in the absence of their cognate antigen, they are able to preserve their quantity through a process of self-renewal. However, it remains unknown how TCR engagement impacts the self-renewal capacity of Tpex in settings of continued antigen exposure. more...