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Items: 4

1.

Histone H2A mono-ubiquitination is a crucial step to mediate PRC1 dependent repression of developmental genes to maintain ES cell identity.

(Submitter supplied) Two distinct Polycomb complexes, PRC1 and PRC2, collaborate to maintain epigenetic repression of key developmental loci in embryonic stem cells (ESCs). PRC1 and PRC2 have histone modifying activities, catalyzing mono-ubiquitination of histone H2A (H2AK119u1) and trimethylation of H3 lysine 27 (H3K27me3) respectively. Compared to H3K27me3, localization and role of H2AK119ub1 is not fully understood in ESCs. more...
Organism:
Mus musculus
Type:
Expression profiling by array; Genome binding/occupancy profiling by array
Platforms:
GPL14573 GPL14597 GPL1261
40 Samples
Download data: CEL, TXT
Series
Accession:
GSE38650
ID:
200038650

PubMed Full text in PMC Similar studies Analyze with GEO2R

2.

ChIP-on-chip analysis of Ring1B, Ring1A, H2AK119u1 and H3K27me3 in mouse ES cells

(Submitter supplied) ChIP-on-chip analysis was carried out to determine targets of Ring1B, Ring1A, H2AK119u1 and H3K27me3 in mouse ES cells.
Organism:
Mus musculus
Type:
Genome binding/occupancy profiling by array
Platforms:
GPL14597 GPL14573
28 Samples
Download data: TXT
Series
Accession:
GSE38504
ID:
200038504

PubMed Full text in PMC Similar studies Analyze with GEO2R

3.

Agilent-014717 Mouse Promoter ChIP-on-Chip Set 244K, Microarray 2 of 2 (G4490A) (Probe Name version)

(Submitter supplied) Mouse Promoter ChIP-on-Chip Set 244K 2 of 2 Arrays of this design have barcodes that begin with 16014717 or 2514717. Orientation: Features are numbered Left-to-Right, Top-to-Bottom as scanned by an Agilent scanner (barcode on the left, DNA on the back surface, scanned through the glass), matching the FeatureNum output from Agilent's Feature Extraction software. The ID column represents the Agilent Probe Name. more...
Organism:
Mus musculus
10 Series
1 Related Platform
26 Samples
Download data
Platform
Accession:
GPL14597
ID:
100014597

4.

H2AK119u1 in Ring1A-KO ESCs (OHT-)_Promoter 2 (rep 2)

Organism:
Mus musculus
Source name:
Input DNA from Ring1A(-/-);Ring1B(fl/fl);R26::CreERT2 ES cells (OHT-untreated) (channel 1) Immunoprecipitated DNA from Ring1A(-/-);Ring1B(fl/fl);R26::CreERT2 ES cells (OHT-untreated) (channel 2)
Platform:
GPL14597
Series:
GSE38504 GSE38650
Download data: TXT
Sample
Accession:
GSM943713
ID:
300943713

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