GSM9797[Accession] - GEO DataSets

Select item 2000023511.

chemotherapy cross-resistance and treatment response in childhood acute lymphoblastic leukemia

(Submitter supplied) Acute lymphoblastic leukemia (ALL) can be cured with combination chemotherapy in over 75% of children, but the cause of treatment failure in the remaining patients is unknown. We determined the sensitivity of ALL cells to individual antileukemic agents in 441 patients, and used a genome-wide approach to identify 45 genes differentially expressed in ALL exhibiting cross-resistance to prednisolone, vincristine, asparaginase and daunorubicin. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL96
129 Samples

Download data: CEL

Series

Accession:: GSE2351

ID:: 200002351

Select item 2000006602.

DNR resistant B-ALL

(Submitter supplied) primary ALL cells (B-lineage) resistant to daunorubicin by the MTT in vitro sensitivity assay Keywords = ALL Keywords: other

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL96
23 Samples

Download data: CEL

Series

Accession:: GSE660

ID:: 200000660

Select item 2000006583.

VCR resistant B-ALL

(Submitter supplied) primary ALL cells (B-lineage) resistant to vincristine by the MTT in vitro sensitivity assay Keywords = ALL Keywords: other

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL96
29 Samples

Download data: CEL

Series

Accession:: GSE658

ID:: 200000658

Select item 2000006564.

PRED resistant B-ALL

(Submitter supplied) primary ALL cells (B-lineage) resistant to prednisolone by the MTT in vitro sensitivity assay Keywords = ALL Keywords: other

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL96
20 Samples

Download data: CEL

Series

Accession:: GSE656

ID:: 200000656

Select item 2000006535.

ASP sensitive B-ALL

(Submitter supplied) primary ALL cells (B-lineage) sensitive to L-asparaginase by the MTT in vitro sensitivity assay Keywords = ALL Keywords: other

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL96
66 Samples

Download data: CEL

Series

Accession:: GSE653

ID:: 200000653

Select item 2000006516.

DNR resistant all ALL

(Submitter supplied) primary ALL cells (B- and T-lineage) resistant to daunorubicin by the MTT in vitro sensitivity assay Keywords = ALL Keywords: other

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL96
28 Samples

Download data: CEL

Series

Accession:: GSE651

ID:: 200000651

Select item 2000006497.

VCR resistant all ALL

(Submitter supplied) primary ALL cells (B- and T-lineage) resistant to vincristine by the MTT in vitro sensitivity assay Keywords = ALL Keywords: other

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL96
36 Samples

Download data: CEL

Series

Accession:: GSE649

ID:: 200000649

Select item 2000006478.

PRED resistant all ALL

(Submitter supplied) primary ALL cells (B- and T-lineage) resistant to prednisolone by the MTT in vitro sensitivity assay Keywords = ALL Keywords: other

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL96
27 Samples

Download data: CEL

Series

Accession:: GSE647

ID:: 200000647

Select item 2000006439.

ASP sensitive all ALL

(Submitter supplied) primary ALL cells (B- and T-lineage) sensitive to L-asparaginase by the MTT in vitro sensitivity assay Keywords = ALL Keywords: other

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL96
81 Samples

Download data: CEL

Series

Accession:: GSE643

ID:: 200000643

Select item 20000063510.

Identification of novel genomic determinants of cellular drug resistance in acute lymphoblastic leukemia.

(Submitter supplied) Cellular drug resistance is associated with an unfavorable prognosis in pediatric acute lymphoblastic leukemia (ALL). To identify genes conferring resistance to antileukemic agents, we analyzed the expression of >12,700 genes in sensitive and resistant ALL cells obtained at diagnosis from 174 patients. This revealed 42, 59, 54 and 22 genes (P≤0.001) that were differentially expressed in B-lineage ALL that was sensitive versus resistant to prednisolone, vincristine, asparaginase or daunorubicin, respectively, with prediction accuracies of 71-76%. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL96
173 Samples

Download data: CEL

Series

Accession:: GSE635

ID:: 200000635

Select item 10000009611.

[HG-U133A] Affymetrix Human Genome U133A Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 08, 2012: annotation table updated with netaffx build 32 June 24, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site The U133 set includes 2 arrays with a total of 44928 entries and was indexed 29-Jan-2002. more...

Organism:: Homo sapiens

364 DataSets
1125 Series
11 Related Platforms
42429 Samples

Download data

Platform

Accession:: GPL96

ID:: 100000096

Select item 30000979712.

nl113

Organism:: Homo sapiens

Source name:: primary acute lymphoblastic leukemia cells

Platform:: GPL96
Series:: GSE635 GSE643 GSE647 GSE649 GSE651 GSE653 GSE656 GSE658 GSE660 GSE2351

Download data: CEL

Sample

Accession:: GSM9797

ID:: 300009797

GEO DataSets

Functional Genomics Studies

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