txid5850[Organism:noexp] - GEO DataSets

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Select item 2001281151.

Malaria Host Pathogen Center Experiment 07A and 07B - Macaca fascicularis infected with Plasmodium knowlesi to produce and integrate clinical, hematological, parasitological, omics, telemetric and histopathological measures of acute primary infection.

(Submitter supplied) This project is part of the Malaria Host-Pathogen Interaction Center (MaHPIC) - a transdisciplinary malaria systems biology research program initially supported by an NIH/NIAID contract (# HHSN272201200031C, 2012-2017; see http://www.systemsbiology.emory.edu). The MaHPIC has continued with support from the Defense Advanced Research Project Agency (DARPA) and others. The MaHPIC generates many data types (e.g., clinical, hematological, parasitological, metabolomics, functional genomics, lipidomics, proteomics, immune response, telemetry) and mathematical models, to iteratively test and develop hypotheses related to the complex host-parasite dynamics in the course of malaria in non-human primates (NHPs), and metabolomics data via collaborations with investigators conducting clinical studies in malaria endemic countries, with the overarching goal of better understanding human disease, pathogenesis, and immunity. more...

Organism:: Plasmodium knowlesi; Macaca fascicularis; Macaca mulatta

Type:: Expression profiling by high throughput sequencing

Platforms:: GPL26280 GPL25695
115 Samples

Download data: FA, GTF, PDF, TXT, XLSX

Series

Accession:: GSE128115

ID:: 200128115

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2001270792.

Malaria Host Pathogen Center Experiment 06: Macaca mulatta infected with Plasmodium knowlesi sporozoites to produce and integrate clinical, hematological, parasitological, omics, telemetric, and histopathological measures of acute primary infection.

Organism:: Macaca mulatta; Plasmodium knowlesi

Type:: Expression profiling by high throughput sequencing

Platform:: GPL25695
47 Samples

Download data: FA, GTF, PDF, TXT, XLSX

Series

Accession:: GSE127079

ID:: 200127079

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2001234953.

Malaria Host Pathogen Interaction Center Experiment 30: Pilot experiment for Macaca mulatta infected with Plasmodium knowlesi Malayan strain sporozoites to produce and integrate measures of acute primary infection.

Organism:: Macaca mulatta; Plasmodium knowlesi

Type:: Expression profiling by high throughput sequencing

Platform:: GPL25695
63 Samples

Download data: FA, GTF, PDF, TXT, XLSX

Series

Accession:: GSE123495

ID:: 200123495

SRA Run Selector

Select item 2001109704.

Malaria Host Pathogen Interaction Center Experiment S01: Host and parasite gene transcript abundances, from cultured cells, of Macaca mulatta infected with Plasmodium knowlesi Pk1(A+), Pk1(B+)1+, Pk1(C+) ex vivo time course.

(Submitter supplied) This project is part of the Malaria Host-Pathogen Interaction Center (MaHPIC) - is a transdisciplinary malaria systems biology research program initially supported by an NIH/NIAID contract (# HHSN272201200031C, 2012-2017; see http://www.systemsbiology.emory.edu). The MaHPIC continues with ongoing support from the Defense Advanced Research Project Agency (DARPA) and others. The MaHPIC generates many data types (e.g., clinical, hematological, parasitological, metabolomics, functional genomics, lipidomics, proteomics, immune response, telemetry) and mathematical models, to iteratively test and develop hypotheses related to the complex host-parasite dynamics in the course of malaria in non-human primates (NHPs), and metabolomics data via collaborations with investigators conducting clinical studies in malaria endemic countries, with the overarching goal of better understanding human disease, pathogenesis, and immunity. more...

Organism:: Macaca mulatta; Plasmodium knowlesi

Type:: Expression profiling by high throughput sequencing

Platform:: GPL25695
9 Samples

Download data: FA, GTF, PDF, TXT, XLSX

Series

Accession:: GSE110970

ID:: 200110970

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2001026955.

Comparative profiling of the heterochromatin landscape in different life cycle stages, strains and species of malaria parasites

(Submitter supplied) Heterochromatin is a tightly packaged form of DNA that leads to permanent or temporal gene silencing. In P. falciparum heterochromatin is formed after trimethylation of lysine 9 on histone H3 and consequent binding of heterochromatin protein 1 (HP1). Genome-wide profiling studies established that in P. falciparum blood stage schizonts heterochromatin is formed at subtelomeres and some intra-chromosomal islands. more...

Organism:: Plasmodium berghei; Plasmodium falciparum; Plasmodium knowlesi; Plasmodium vivax; Plasmodium chabaudi; Plasmodium yoelii

Type:: Genome binding/occupancy profiling by high throughput sequencing

6 related Platforms
26 Samples

Download data: BEDGRAPH

Series

Accession:: GSE102695

ID:: 200102695

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2000942746.

An Integrated Approach to Understanding Host-Pathogen Interactions

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Macaca mulatta; Plasmodium coatneyi; Plasmodium cynomolgi strain B; Plasmodium cynomolgi ceylonensis; Macaca fascicularis; Plasmodium knowlesi

Type:: Expression profiling by high throughput sequencing

7 related Platforms
556 Samples

Download data

Series

Accession:: GSE94274

ID:: 200094274

PubMed Full text in PMC Similar studies

Select item 2000628867.

Plasmodium knowlesi gene expression differs in ex vivo compared to in vitro blood-stage cultures

(Submitter supplied) The purpose of this reasearch is to identify and evaluate the global gene expression of Plasmodium knowlesi blood-stage parasites and specifically compare the gene expression profiles of samples derived from ex vivo versus long-term in vitro cultures.

Organism:: Plasmodium knowlesi

Type:: Expression profiling by array

Platform:: GPL19374
21 Samples

Download data: GPR, TXT

Series

Accession:: GSE62886

ID:: 200062886

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 1000346918.

Illumina NovaSeq 6000 (Plasmodium knowlesi)

Organism:: Plasmodium knowlesi

Download data

Platform

Accession:: GPL34691

ID:: 100034691

Select item 1000262809.

Illumina HiSeq 3000 (Macaca fascicularis; Plasmodium knowlesi)

Organism:: Plasmodium knowlesi; Macaca fascicularis

2 Series
109 Samples

Download data

Platform

Accession:: GPL26280

ID:: 100026280

Select item 10002569510.

Illumina HiSeq 3000 (Macaca mulatta; Plasmodium knowlesi)

Organism:: Plasmodium knowlesi; Macaca mulatta

5 Series
125 Samples

Download data

Platform

Accession:: GPL25695

ID:: 100025695

Select item 10002391511.

Illumina NextSeq 500 (Plasmodium knowlesi)

Organism:: Plasmodium knowlesi

1 Series
4 Samples

Download data

Platform

Accession:: GPL23915

ID:: 100023915

Select item 10001937412.

ZB/SBS-NTU Plasmodium knowlesi 11.6K v1

(Submitter supplied) Long oligonucleotides were selected using the program OligoRankPick, described in Guangan Hu, Manuel Llinás, Jingguang Li, Peter Rainer Preiser & Zbynek Bozdech: Selection of long oligonucleotides for gene expression microarrays using weighted rank-sum strategy. BMC Bioinformatics 2007, 8:350. The 60-bp oligonucleotides were spotted onto poly-L-lysine-coated microscopic slides as described in Zbynek Bozdech, Jingchun Zhu, Marcin P Joachimiak, Fred E Cohen, Brian Pulliam & Joseph L DeRisi: Expression profiling of the schizont and trophozoite stages of Plasmodium falciparum with a long-oligonucleotide microarray. more...