GEO DataSet Links for BioProject (Select 101291) - GEO DataSets

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Items: 2

Select item 2000083141.

Characterization of weight loss and weight regain mechanisms after Roux-en-Y gastric bypass in rats

(Submitter supplied) Roux-en-Y gastric bypass (RYGB) is the most effective therapy for morbid obesity, but it has a ~20% failure rate. We used our established RYGB model in diet-induced obese (DIO) Sprague-Dawley rats, which reproduces human bi-phasic body weight (BW) loss pattern, to determine mechanisms contributing to success (RGYB-S) or failed (RYGB-F) RYGB. DIO rats were randomized to RYGB, sham operated Obese, and sham operated obese pair fed-linked to RYGB (PF) groups. more...

Organism:: Rattus norvegicus

Type:: Expression profiling by array

Dataset:: GDS2956
Platform:: GPL1355
18 Samples

Download data: CEL, CHP

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Accession:: GSE8314

ID:: 200008314

Select item 29562.

Roux-en-Y gastric bypass model

Analysis of subcutaneous abdominal fat and hypothalami of male Sprague-Dawleys that lost or regained weight after Roux-en-Y gastric bypass (RYGB) surgery. Obesity induced by diet prior to RYBG. Results provide insight into the mechanisms contributing to successful weight loss following RYBG.