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Links from GEO DataSets

Items: 13

1.
Full record GDS182

Large-scale analysis of the mouse transcriptome (MG-U74A)

Gene expression profiles from a diverse array of tissues, organs, and cell lines, from the normal physiological state. Represents a preliminary description of the normal mammalian transcriptome.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 45 tissue sets
Platform:
GPL32
Series:
GSE97
90 Samples
Download data: CEL
2.
Full record GDS4138

Proteasomal inhibitor lactacystin effect on cortical neurons in vitro: time course (MG_U74A)

Analysis of cultured cortical neurons treated with 1uM lactacystin for up to 48 hr. Lactacystin induces neuronal apoptosis. Results provide insight into molecular mechanisms underlying proteasomal inhibition-induced neuronal death.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 agent, 2 time sets
Platform:
GPL32
Series:
GSE22465
4 Samples
Download data: CEL
DataSet
Accession:
GDS4138
ID:
4138
3.
Full record GDS2440

Dendritic cell development in vitro

Analysis of dendritic cell (DC) development from Flt3(+)CD11b(+) DC progenitors. DC progenitors treated with GM-CSF for 7 and 10 days to induce differentiation. DCs differentiated for 10 days were subsequently treated with TNFalpha to induce maturation.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 4 protocol sets
Platform:
GPL32
Series:
GSE575
4 Samples
Download data
DataSet
Accession:
GDS2440
ID:
2440
4.
Full record GDS2053

1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned substantia nigra: time course

Analysis of substantia nigrae (SN) injured by treatment with the dopaminergic neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine at 1 and 7 days postlesion. Parkinson's disease (PD) culminates in the loss of dopaminergic neurons of the SN. Results provide insight into the pathogenesis of PD.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 2 agent, 3 time sets
Platform:
GPL32
Series:
GSE4788
12 Samples
Download data: CEL
5.
Full record GDS1593

p38 inhibitor PD169316 effect on embryonic stem derived differentiated cells (U74A Version 1)

Analysis of embryonic stem cells differentiated in the presence of PD169316, an inhibitor of p38 that blocks apoptosis without altering differentiation. Results identify gene families whose transcriptional regulation correlates with cell fate: differentiation with or without apoptosis.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 agent, 2 cell line sets
Platform:
GPL32
Series:
GSE2042
6 Samples
Download data: CEL, EXP
DataSet
Accession:
GDS1593
ID:
1593
6.
Full record GDS1374

Stearoyl-CoA desaturase 1 null mutation effect on liver

Analysis of liver of 6 week old stearoyl-CoA desaturase 1 (SCD1) knockout females. SCD1 is a lipogenic enzyme that catalyzes the synthesis of monosaturated fatty acids. SCD1 null mutants have reduced body adiposity, increased insulin sensitivity, and are resistant to diet-induced weight gain.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 genotype/variation sets
Platform:
GPL32
Series:
GSE2926
10 Samples
Download data: CEL, EXP
7.
Full record GDS1015

Serum response factor SRF induction in embryonic stem cells: time course

Expression profiling of embryonic stem (ES) cells following stimulation with fetal bovine serum at various time points up to 180 minutes. Expression in wild type ES cells compared to that in Srf homozygous mutants with or without an SRF transgene. Results identify potential targets of SRF.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 genotype/variation, 2 protocol, 5 time sets
Platform:
GPL32
Series:
GSE1949
15 Samples
Download data
DataSet
Accession:
GDS1015
ID:
1015
8.
Full record GDS1014

Serum response factor SRF overexpression in embryonic stem cells

Expression profiling of embryonic stem (ES) cells overexpressing serum response factor SRF. SRF transiently transfected into ES cells disrupted for both copies of SRF. RNA examined 72 hours after transfection. Results identify potential transcriptional targets of SRF.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 3 agent, 4 genotype/variation sets
Platform:
GPL32
Series:
GSE1948
23 Samples
Download data
DataSet
Accession:
GDS1014
ID:
1014
9.
Full record GDS703

Dystrophin-deficient mdx extraocular and leg muscle

Analysis of extraocular (EOM) and hindlimb (gastrocnemius/soleus) muscle in mdx (dystrophin-deficient; Duchenne muscular dystrophy model) mice at postnatal day 56.5. Highly specific changes observed between dystrophic (leg) and spared (EOM) muscle.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 strain, 2 tissue sets
Platform:
GPL32
Series:
GSE1472
20 Samples
Download data: CEL
DataSet
Accession:
GDS703
ID:
703
10.
Full record GDS702

Extraocular, limb, and masticatory muscle comparison

Comparison of extraocular (EOM), masticatory (masseter), and hindlimb (gastrocnemius/soleus) muscle in 8 week old mice. EOM defined by distinct gene expression profile.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 3 tissue sets
Platform:
GPL32
Series:
GSE1062
14 Samples
Download data: CEL
11.
Full record GDS487

Cardiomyopathy, severe dilated

Examination of ventricles of 10 week mice overexpressing dominant-negative (dn) small GTP binding protein p21ras. dn-p21ras mice show severe cardiac dilation and decreased contractility. p21ras implicated in hypertrophic response of cardiomyocytes.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 genotype/variation sets
Platform:
GPL32
Series:
GSE760
6 Samples
Download data: CEL
DataSet
Accession:
GDS487
ID:
487
12.
Full record GDS432

MHC class II transactivator targets (MG-U74Av1)

Identification of new targets of major histocompatibility complex class II transactivator CIITA in dendritic cells (DC). Day 10 bone marrow-derived DCs isolated from B6 background CIITA-deficient, MHC class II-deficient and wild type mice examined.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 3 strain sets
Platform:
GPL32
Series:
GSE557
3 Samples
Download data
DataSet
Accession:
GDS432
ID:
432
13.
Full record GDS233

Muscle regeneration (U74Av1)

Cardiotoxin injected into mouse gastrocnemius muscle to induce muscle regeneration. Muscles profiled at 27 time points (0-40 days) post-injection. Transcriptional regulatory pathways defined.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 6 time sets
Platform:
GPL32
Series:
GSE469
12 Samples
Download data: CEL
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