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Links from GEO DataSets

Items: 4

1.

Amplification and overexpression of E2F3 in human bladder cancer.

(Submitter supplied) We demonstrate that, in human bladder cancer, amplification of the E2F3 gene, located at 6p22, is associated with overexpression of its encoded mRNA transcripts and high levels of expression of E2F3 protein. Immunohistochemical analyses of E2F3 protein levels have established that around one-third (33/101) of primary transitional cell carcinomas of the bladder overexpress nuclear E2F3 protein, with the proportion of tumours containing overexpressed nuclear E2F3 increasing with tumour stage and grade. more...
Organism:
Homo sapiens
Type:
Genome variation profiling by array
Platforms:
GPL4483 GPL4482 GPL3898
10 Samples
Download data
Series
Accession:
GSE6123
ID:
200006123

PubMed Similar studies Analyze with GEO2R

2.

Gene expression analysis & Comparative genomic hybridization from Lung cancer Cell lines

(Submitter supplied) Gene expression and Comparative genomic hybridization (CGH) microarrays performed in a set of 8 Lung cancer Cell lines.
Organism:
Homo sapiens
Type:
Expression profiling by array; Genome variation profiling by array
Platform:
GPL1998
16 Samples
Download data: GPR
Series
Accession:
GSE14079
ID:
200014079

PubMed Similar studies Analyze with GEO2R

3.

Waldman Bladder tumors

(Submitter supplied) 80 bladder tumors of different stages, grades and histologies analyzed on costom made cDNA arrays with 10638 gene elements Keywords: parallel sample
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL1479
80 Samples
Download data
Series
Accession:
GSE1827
ID:
200001827

PubMed Similar studies Analyze with GEO2R

4.

Role of E2F3 expression in human bladder and prostate cancer cells

(Submitter supplied) Amplification and overexpression of the E2F3 gene at 6p22 in human bladder cancer is associated with increased tumour stage, grade and proliferation index, and in prostate cancer E2F3 overexpression is linked to tumour aggressiveness. We first used small interfering RNA technology to confirm the potential importance of E2F3 overexpression in bladder cancer development. Knockdown of E2F3 expression in bladder cells containing the 6p22 amplicon strongly reduced the extent of bromodeoxyuridine (BrdU) incorporation and the rate of cellular proliferation. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL3904
3 Samples
Download data
Series
Accession:
GSE6131
ID:
200006131

PubMed Similar studies Analyze with GEO2R

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