GEO DataSets

(Submitter supplied) Using Affymetrix microarray technology we analyzed the gene expression profiles of the most important pathological categories of bladder cancer in order to detect potential marker genes. Applying an unsupervised cluster algorithm we observed clear differences between tumor and control samples, as well as between superficial and muscle invasive tumors. According to cluster results, the T1 high grade tumor type presented a global genetic profile which could not be distinguished from invasive cases. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL570

12 Samples

Download data: CEL

(Submitter supplied) The aims of this study were to determine the impact of different levels of RNA degradation as well as to ascertain if the gene expression profiles obtained from bladder washing correlates to that obtained from the related bladder tumor. Keywords: RNA degradation, bladder washing, bladder tumor, bladder cancer

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL2767

16 Samples

Download data

(Submitter supplied) 80 bladder tumors of different stages, grades and histologies analyzed on costom made cDNA arrays with 10638 gene elements Keywords: parallel sample

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL1479

80 Samples

Download data

(Submitter supplied) The whole-genome oligonucleotide microarray analysis of peripheral blood samples can contribute to the determination of distant blood markers of local pathophysiological alterations in colorectal diseases. These markers can lead to alternative screening procedures. Keywords: whole genomic expression

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL570

30 Samples

Download data: CEL

(Submitter supplied) Gene expression profile based classification of colonic diseases are suitable for identification of diagnostic mRNA expression patterns which can establish the basis of a new molecular biological diagnostic method Keywords: whole genomic expression

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL570

33 Samples

Download data: CEL

(Submitter supplied) Bladder tumours used to construct a tumour stage classifier Keywords = bladder cancer, disease stages, classification Keywords: other

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS183

Platform:

GPL80

40 Samples

Download data: CEL

(Submitter supplied) Expression profiling of superficial bladder tumours to delineate the expression pattern differences between non-recurring and recurring tumours. Keywords = bladder cancer, superficial, recurrence, prediction Keywords: other

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL80

31 Samples

Download data: CEL

Identification of clinically relevant subclasses of bladder carcinoma. Three major stages identified, Ta, T1 and T2-4. Ta tumors further classified into subgroups. A 32-gene molecular classifier was built.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 3 disease state, 4 tissue sets

Platform:

GPL80

Series:

GSE89

40 Samples

Download data: CEL

(Submitter supplied) To better understand the molecular mechanism that underlay tumorigenesis and progression of prostate cancer (PCa), we studied the gene expression profiles of sixteen PCa compared to their matched normal tissues. Using Significance Analysis of Microarrays, we identified 53 genes differentially expressed that were more than 2 fold up- or down-regulated in at least 50 % of the tumors. Keywords: disease state analysis

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL1998

16 Samples

Download data: GPR

(Submitter supplied) Gene expression profile of Transgenic Adenocarcinoma of the Mouse Prostate (TRAMP) reveals murine targets for preclinical development of human prostate cancer therapy In this study, we have generated an open source TRAMP microarray dataset to identify differentially expressed genes from human prostate cancer that have concordant expression in TRAMP tumors, and thereby represent lead targets for preclinical therapy development. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL1261

18 Samples

Download data: CEL

(Submitter supplied) Background: Current diagnosis and treatment of urinary bladder cancer (BC) has shown great progress with the utilization of microarrays. Purpose: Our goal was to identify common differentially expressed (DE) genes among clinically relevant subclasses of BC using microarrays. Methodology/Principal Findings: BC samples and controls, both experimental as well as publicly available datasets, were analyzed by whole genome microarrays. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL2895

15 Samples

Download data: TXT

(Submitter supplied) The aim of the study was to identify markers for the early diagnosis of endoprosthesis loosening, for the differentiation between wear-particle induced and septic loosening, as well as to gather new insights into the pathogenesis. 824 genes were differentially expressed with a fold change greater than 2. Among these were Chitinase 1, CD52, Calpain 3, Apolipoprotein, CD18, Lysyl oxidase, Cathepsin D, E-Cadherin, VE-Cadherin, Nidogen, Angiopoietin 1 and Thrombospondin 2, and the differential expression levels were validated by RT-PCR. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL96

10 Samples

Download data: CEL, EXP

(Submitter supplied) A bovine oligo microarray platform (GPL7053) was used to profile gene expression from twenty-five (25) bovine biceps brachii samples randomly collected at the slaughterhouse. Four (4) of these animals were suspected for corticosteroids treatment at tymus histological analyses. Eighteen (18) negative controls animals were also included. Analysis with PAM (Prediction Analysis of Microarray) identified ten (10) genes as potential biomarkers that best discriminated control animals from the animals suspected for corticosteroids treatment.

Organism:

Bos taurus

Type:

Expression profiling by array

Platform:

GPL7053

43 Samples

Download data: TXT

(Submitter supplied) Abstract: Bladder cancer is one of the most common cancers and, together with prostate carcinoma, accounts for the majority of the malignancies of the genitourinary tract. Since prognosis ameliorates with early detection, it will be beneficial to have a repertoire of diagnostic markers that could complement the current diagnosis protocols. Recently, cell-secreted extracellular vesicles have received great interest as a source of low invasive disease biomarkers because they are found in many body fluids, including urine. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS5649

Platform:

GPL10558

11 Samples

Download data: TXT

Analysis of extracellular vesicles (EVs) from the urine of bladder cancer (BC) patients. Results provide insight into the potential use of mRNAs associated with urinary EVs as non-invasive diagnostic biomarkers of BC.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 2 disease state sets

Platform:

GPL10558

Series:

GSE51843

11 Samples

Download data

(Submitter supplied) The gene expression profile of blood drawn from healthy individuals was studied over a period of six months, at five time points. The gene expression profiles appeared to be constant over one month and to slightly vary over three months. A small proportion of genes were found to be differentially regulated according to gender. Differential gene regulation by age (in subjects 25–55 years of age versus subjects > 55 years of age) was not observed. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL570

109 Samples

Download data: CEL