GEO DataSets

(Submitter supplied) Mutation generates the heritable variation that genetic drift and natural selection shape. In classical quantitative genetic models, drift is a function of the effective population size and acts uniformly across traits, while mutation and selection act trait-specifically. We identified thousands of quantitative trait loci (QTL) influencing transcript abundance traits in a cross of two C. elegans strains; although trait-specific mutation and selection explained some of the observed pattern of QTL distribution, the pattern was better explained by trait-independent variation in the intensity of selection on linked sites. more...

Organism:

Caenorhabditis elegans

Type:

Expression profiling by array

Platform:

GPL7727

208 Samples

Download data: TXT

(Submitter supplied) Complex traits, including common disease-related traits, are affected by many different genes that function in multiple pathways and networks. The apoptosis, MAPK, Notch and Wnt signalling pathways play important roles in development and disease progression. At the moment we have a poor understanding of how allelic variation affects gene expression in these pathways at the level of translation. Here we report the effect of natural genetic variation on transcript and protein abundance involved in developmental signalling pathways in Caenorhabditis elegans. more...

Organism:

Caenorhabditis elegans

Type:

Expression profiling by array

Platform:

GPL10094

78 Samples

Download data: TXT

(Submitter supplied) Transcriptomic analysis on 207 genetically distinct C. elegans wild strains

Organism:

Caenorhabditis elegans

Type:

Expression profiling by high throughput sequencing

Platform:

GPL26672

609 Samples

Download data: TSV