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Links from GEO DataSets

Items: 20

1.

Expression data from HPV(-) and HPV(+) squamous cell carcinoma cell lines

(Submitter supplied) Oncogenic human papillomaviruses (HPVs) are associated with nearly all carcinomas of the uterine cervix and have also become an increasingly important factor in the etiology of a subset of oropharyngeal tumors. HPV-associated head and neck cancers (HNSCCs) have a distinct risk profile and appreciate a prognostic advantage compared to HPV-negative HNSCC. We analyzed the genome-wide expression patterns in two HPV(+) and two HPV(-) squamous cell carcinoma (SCC) cell lines.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL570
4 Samples
Download data: CEL
Series
Accession:
GSE24089
ID:
200024089
2.

Expression and methylation analyses of HPV(-) and HPV(+) squamous cell carcinoma cell lines

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Methylation profiling by array; Expression profiling by array; Methylation profiling by genome tiling array
9 related Platforms
36 Samples
Download data: CEL
Series
Accession:
GSE24091
ID:
200024091
3.

Genome-wide methylation analysis in HPV(-) and HPV(+) squamous cell carcinoma cell lines

(Submitter supplied) HPV-associated head and neck cancers (HNSCCs) have a distinct risk profile and appreciate a prognostic advantage compared to HPV-negative HNSCC. To assess the genome-wide methylation changes in HPV(+) and HPV(-) tumors, we analyzed DNA methylation and expression patterns in two HPV(+) and two HPV(-) cell lines. HPV(+) tumors have overall higher DNA methylation in genic and LINE1 regions than HPV(-) tumors, and polycomb repressive complex 2 (PRC2) targets tend to be much more highly methylated in HPV(+) cells.
Organism:
Homo sapiens
Type:
Methylation profiling by genome tiling array
7 related Platforms
28 Samples
Download data: BED, CEL, TXT
Series
Accession:
GSE24090
ID:
200024090
4.

Epigenome analysis in HPV(-) and HPV(+) squamous cell carcinoma cell lines

(Submitter supplied) Human papillomavirus (HPV)-associated head and neck cancers (HNSCCs) have a distinct risk profile and appreciate a prognostic advantage compared to HPV-negative HNSCC. Promoter hypermethylation has been widely recognized as an important mechanism in the progression of HNSCC, but the extent to which this mechanism is consistent between HPV(+) and HPV(-) tumors is unknown. To assess the genome-wide methylation changes in HPV(+) and HPV(-) tumors, we analyzed DNA methylation and expression patterns in two HPV(+) and two HPV(-) cell lines. more...
Organism:
Homo sapiens
Type:
Methylation profiling by array
Platform:
GPL8490
4 Samples
Download data: TXT
Series
Accession:
GSE24087
ID:
200024087
5.

FF and FFPE HPV+ and HPV- HNSCC and HNSCC cell lines

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Methylation profiling by array
Platform:
GPL13534
72 Samples
Download data
Series
Accession:
GSE38271
ID:
200038271
6.

450k Analysis of 3 FF HPV+ and 3 FF HPV- HNSCC samples

(Submitter supplied) The methylation analysis of 3 FF HPV+ HNSCC samples and 21 FP HPV- HNSCC samples by Infinium HumanMethylation450 BeadChip
Organism:
Homo sapiens
Type:
Methylation profiling by array
Platform:
GPL13534
6 Samples
Download data: CSV
Series
Accession:
GSE38268
ID:
200038268
7.

450k Analysis of 42 FFPE HPV+ and HPV- HNSCC samples

(Submitter supplied) The methylation analysis of 21 FFPE HPV+ HNSCC samples and 21 FPPE HPV- HNSCC samples by Infinium HumanMethylation450 BeadChip
Organism:
Homo sapiens
Type:
Methylation profiling by array
Platform:
GPL13534
42 Samples
Download data: CSV
Series
Accession:
GSE38266
ID:
200038266
8.

Methylome Analysis of FF HPV+ and HPV- HNSCC samples

(Submitter supplied) The analysis of the 6 methylomes by MeDIP-Seq comprise 3 HPV+ HNSCC samples and 3 HPV- HNSCC samples
Organism:
Homo sapiens
Type:
Methylation profiling by high throughput sequencing
Platform:
GPL9115
6 Samples
Download data: WIG
Series
Accession:
GSE38263
ID:
200038263
9.

Unique DNA methylation signature in HPV-positive head and neck squamous cell carcinomas

(Submitter supplied) Background. Head and neck squamous cell carcinomas (HNSCCs) represent a heterogeneous group of cancers, for which human papilloma virus (HPV) infection is an emerging risk factor. Previous studies showed promoter hypermethylation in HPV(+) oropharyngeal cancers, but only few consistent target genes have been so far described and the evidence of a functional impact on gene expression is still limited. more...
Organism:
Homo sapiens
Type:
Methylation profiling by genome tiling array
Platform:
GPL13534
11 Samples
Download data: IDAT
Series
Accession:
GSE95036
ID:
200095036
10.

RNA-seq and DNA methylation analysis in head and neck cancer cells and cell lines

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing; Methylation profiling by array
Platforms:
GPL13534 GPL18460
25 Samples
Download data
Series
Accession:
GSE98811
ID:
200098811
11.

DNA methylation analysis in head and neck cancer cells

(Submitter supplied) DNA methylation analysis in oropharyngeal squamous carcinoma(OPSCC) samples, oropharyngeal non-cancerous mucosa samples and head and neck cancer cell lines, FaDu and UMSCC47 before and after 5-aza'2-deoxycytidine(Aza)/trichostatin A(TSA) treatment. Infinium HumanMethylation450 BeadChip was used to obtain DNA methylation profiles across 485,577 CpG sites. Samples included 13 OPSCC samples, 4 non-cancerous mucosa samples and 2 FaDu with and without Aza/TSA treatment and 2 UMSCC47 with and without Aza/TSA treatment.
Organism:
Homo sapiens
Type:
Methylation profiling by array
Platform:
GPL13534
21 Samples
Download data: TXT
Series
Accession:
GSE98807
ID:
200098807
12.

RNA-seq of head and neck cancer cell lines

(Submitter supplied) Transcriptome analysis in head and neck cancer cell lines, FaDu and UMSCC47 with and without 5-aza'2-deoxycytidine(Aza)/trichostatin A(TSA) treatment.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL18460
4 Samples
Download data: TXT
Series
Accession:
GSE98805
ID:
200098805
13.

Genome wide DNA methylation in oral squamous cell carcinoma (OSCC) disease and adjacent normal tissue samples

(Submitter supplied) Genome wide DNA methylation profiling of normal and adjacent OSCC samples. The Illumina Infinium 450k Human DNA methylation Beadchip v1.2 was used to obtain DNA methylation profiles across approximately 4,50,000 CpGs in tissue samples. Total 21 samples were taken including 10 paired and 1 unpaired tissues. 6 were HPV Positive and 5 were HPV negative.
Organism:
Homo sapiens
Type:
Methylation profiling by genome tiling array
Platform:
GPL13534
21 Samples
Download data: IDAT
Series
Accession:
GSE87053
ID:
200087053
14.

FOXM1 Orchestrates a Global Methylation Signature that Mimics the Cancer Epigenome

(Submitter supplied) Aberrant upregulation of a single oncogene FOXM1 in primary normal human oral epithelial cells orchestrated a cancer-like methylome landscape This study have identified a unique FOXM1-induced epigenetic signature which may have potentials as biomarkers for early oral cancer screening, diagnostic and/or therapeutic interventions
Organism:
Homo sapiens
Type:
Methylation profiling by genome tiling array
Platform:
GPL14361
3 Samples
Download data: GFF, PAIR, TXT
Series
Accession:
GSE31767
ID:
200031767
15.

MeDIP-chip from head and neck squamous cell carcinoma tissues and normal subjects

(Submitter supplied) Profiling the genome-wide methylation status of head and neck squamous cell carcinoma and normal subjects
Organism:
Homo sapiens
Type:
Methylation profiling by genome tiling array
Platform:
GPL16062
6 Samples
Download data: PAIR
Series
Accession:
GSE58630
ID:
200058630
16.

Global hypomethylation identifies loci targeted for hypermethylation in head and neck cancer

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Methylation profiling by array
Platform:
GPL8490
322 Samples
Download data
Series
Accession:
GSE25093
ID:
200025093
17.

Global hypomethylation identifies loci targeted for hypermethylation in head and neck cancer: blood controls

(Submitter supplied) Genome-wide DNA methylation profiling of head and neck squamous cell carcinomas (HNSCCs). The Illumina Infinium 27k Human DNA methylation BeadChip v1.2 was used to obtain DNA methylation profiles across approximately 27,000 CpGs in fresh-frozen tumor tissues. Samples included 91 tumors from the oralpharynx and larynx, reflecting all stages of disease, 18 normal head and neck National Disease Research Interchange (NDRI) samples, and 213 normal control blood samples.
Organism:
Homo sapiens
Type:
Methylation profiling by array
Platform:
GPL8490
213 Samples
Download data: TXT
Series
Accession:
GSE25091
ID:
200025091
18.

Global hypomethylation identifies loci targeted for hypermethylation in head and neck cancer: HNSCC

(Submitter supplied) Genome-wide DNA methylation profiling of head and neck squamous cell carcinomas (HNSCCs). The Illumina Infinium 27k Human DNA methylation BeadChip v1.2 was used to obtain DNA methylation profiles across approximately 27,000 CpGs in fresh-frozen tumor tissues. Samples included 91 tumors from the oralpharynx and larynx, reflecting all stages of disease, 18 normal head and neck National Disease Research Interchange (NDRI) samples, and 213 normal control blood samples.
Organism:
Homo sapiens
Type:
Methylation profiling by array
Platform:
GPL8490
91 Samples
Download data: TXT
Series
Accession:
GSE25089
ID:
200025089
19.

Global hypomethylation identifies loci targeted for hypermethylation in head and neck cancer: normal head and neck tissue

(Submitter supplied) Genome-wide DNA methylation profiling of head and neck squamous cell carcinomas. The Illumina Infinium 27k Human DNA methylation BeadChip v1.2 was used to obtain DNA methylation profiles across approximately 27,000 CpGs in fresh-frozen tumor tissues. Samples included 91 tumors from the oralpharynx and larynx, reflecting all stages of disease, 18 normal head and neck National Disease Research Interchange (NDRI) samples, and 213 normal control blood samples.
Organism:
Homo sapiens
Type:
Methylation profiling by array
Platform:
GPL8490
18 Samples
Download data: TXT
Series
Accession:
GSE25083
ID:
200025083
20.

450k Analysis of 24 HNSCC cell lines

(Submitter supplied) The methylation analysis of HPV+ HNSCC cell lines and HPV- HNSCC cell lines as well as clones from an infected HPV- cell line by Infinium HumanMethylation450 BeadChip
Organism:
Homo sapiens
Type:
Methylation profiling by array
Platform:
GPL13534
24 Samples
Download data: CSV
Series
Accession:
GSE38270
ID:
200038270
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