Similar studies for GEO DataSets (Select 200025633) - GEO DataSets

Select item 2000256331.

Transcriptional profiling of C. elegans DAF-19 uncovers a ciliary base-associated protein and a CDK/CCRK/LF2p-related kinase required for intraflagellar transport.

(Submitter supplied) Cilia are ubiquitous cell surface projections that modulate various sensory- and motility based processes and are implicated in a growing number of multi-organ genetic disorders termed ciliopathies. As new components required for cilium biogenesis and function remain unidentified, we sought to further define and validate the transcriptional targets of the ciliogenic C. elegans RFX transcription factor DAF-19. more...

Organism:: Caenorhabditis elegans

Type:: Expression profiling by array

Platform:: GPL200
12 Samples

Download data: CEL

Series

Accession:: GSE25633

ID:: 200025633

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000065632.

Analysis of expression of genes regulated by DAF-19

(Submitter supplied) By screening for genes possessing canonical X-box sequences in promoters of three Caenorhabditis species, namely C. elegans, C. briggsae and C. remanei, we identified 93 genes (including known X-box regulated genes) that encode putative components of ciliated neurons in C. elegans and are subject to the same regulatory control. For many of these genes, restricted anatomical expression in ciliated cells was confirmed, and control of transcription by the ciliogenic DAF-19 RFX transcription factor was demonstrated by comparative transcriptional profiling of daf-19(+) and daf-19(-) animals. more...

Organism:: Caenorhabditis elegans

Type:: Expression profiling by array

Dataset:: GDS2549
Platform:: GPL200
4 Samples

Download data: CEL

Series

Accession:: GSE6563

ID:: 200006563

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 25493.

Transcription factor DAF-19 deficient mutants

Analysis of mutants lacking DAF-19, a transcription factor that regulates genes involved in cilia function. Cilia defects are associated with a variety of human disorders, such as cystic kidney disease. Results provide insight into the mechanisms that regulate the formation and function of cilia.

Organism:: Caenorhabditis elegans

Type:: Expression profiling by array, count, 2 genotype/variation sets

Platform:: GPL200
Series:: GSE6563
4 Samples

Download data: CEL

DataSet

Accession:: GDS2549

ID:: 2549

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 2000960684.

The RFX transcription factor gene, daf-19, has dual funcitons in ciliated and non-ciliated neurons

(Submitter supplied) Cilia are required for many sensory and motility related functions and are involved in growing number of genetic disorders termed ciliopathies. DAF-19, RFX type transcription factor controls expression of many cilia structure and function related genes. To this end, transcriptional profiling of daf-19 mutants (which do not form cilia) and wild-type animals was performed using selectively staged larval stages where cilia mature and maintained, structurally as well as functionally.

Organism:: Caenorhabditis elegans

Type:: Expression profiling by array

Platform:: GPL200
14 Samples

Download data: CEL

Series

Accession:: GSE96068

ID:: 200096068

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000419435.

C. elegans daf-10(m79) mutants vs wild-type worms

(Submitter supplied) Transcriptional profiling of whole day 1 adult C. elegans, comparing animals carrying the m79 mutation in the daf-10 gene and wild-type isogenic animals. Genes that act downstream of sensory neurons to influence longevity, dauer formation and pathogen responses in Caenorhabditis elegans Manuscript abstract:

Organism:: Caenorhabditis elegans

Type:: Expression profiling by array

Platform:: GPL9450
3 Samples

Download data: GPR

Series

Accession:: GSE41943

ID:: 200041943

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000218516.

Gene Expression Profiling of C. elegans - ets-4 Mutant Animals Vs Wild-type

(Submitter supplied) The gene expression profile of WT (N2) C. elegans were compared to that of ets-4(ok165) and ets-4(uz1) mutant animals

Organism:: Caenorhabditis elegans

Type:: Expression profiling by array

Dataset:: GDS3747
Platform:: GPL7272
6 Samples

Download data: TXT

Series

Accession:: GSE21851

ID:: 200021851

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 37477.

Transcription factor ETS-4 deletion effect on larvae

Analysis of stage L4 larvae with two distinct deletion alleles of ets-4: ets-4(ok165) and ets-4(uz1). Adults with ets-4 mutations have a significant extension of mean life span. Results provide insight into the transcriptional control of aging effectors by the ETS-4 transcription factor.

Organism:: Caenorhabditis elegans

Type:: Expression profiling by array, log2 ratio, 2 genotype/variation sets

Platform:: GPL7272
Series:: GSE21851
6 Samples

Download data: TXT

DataSet

Accession:: GDS3747

ID:: 3747

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 2001685978.

Impairing one sensory modality enhances another by reprogramming peptidergic circuits in Caenorhabditis elegans.

(Submitter supplied) Abstract: Animals that lose one sensory modality often show augmented responses to other sensory inputs. The mechanisms underpinning this cross-modal plasticity are poorly understood. To probe these mechanisms, we perform a forward genetic screen for mutants with enhanced O2 perception in C. elegans. Multiple mutants exhibiting increased responsiveness to O2 concomitantly show defects in other sensory responses. more...

Organism:: Caenorhabditis elegans

Type:: Expression profiling by high throughput sequencing

Platform:: GPL22765
10 Samples

Download data: XLSX

Series

Accession:: GSE168597

ID:: 200168597

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2002379379.

Sex-Specific Developmental Gene Expression Atlas Unveils Dimorphic Gene Networks in C. elegans

(Submitter supplied) Sex-specific traits and behaviors are facilitated by the acquisition of unique properties in the nervous system of each sex during development and continues in adulthood. However, the genetic events responsible for introducing these sex-specific features remain poorly understood. In this study, we created a comprehensive gene expression atlas for both sexes of the nematode Caenorhabditis elegans across development. more...

Organism:: Caenorhabditis elegans

Type:: Expression profiling by high throughput sequencing

Platform:: GPL19757
40 Samples

Download data: XLSX

Series

Accession:: GSE237937

ID:: 200237937

PubMed Full text in PMC Similar studies

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