Similar studies for GEO DataSets (Select 200030884) - GEO DataSets

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Items: 16

Select item 2000308841.

Gene expression profiles of Hodgkin’s lymphoma cells after treatment with vorinostat

(Submitter supplied) By using high-density DNA microarrays, we analyzed the gene-expression profile of Hodgkin's lymphoma cell line L-540 after tretament with the histone deactelyse inhibitor vorinostat. Kewitz et al., submitted

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL96
2 Samples

Download data: CEL

Series

Accession:: GSE30884

ID:: 200030884

Select item 2000263252.

Gene expression profiles of Hodgkin’s lymphoma cell lines with different sensitivity to cytotoxic drugs

(Submitter supplied) By using high-density DNA microarrays, we analyzed the gene-expression profile of Hodgkin's lymphoma cell lines. Furthermore, we tested the sensitivity of these cell lines for cytotoxic drugs (cisplatin, etoposide, melphalan) and compared the gene-expression profile of chemotherapy-resistant and -sensitive cell lines. Staege et al., Exp Hematol 2008;36:886-896

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL96
6 Samples

Download data: CEL

Series

Accession:: GSE26325

ID:: 200026325

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000280793.

Classical Hodgkin lymphoma shows epigenetic features of an abortive plasma cellular differentiation: expression of PCM vs. B-cell lines

(Submitter supplied) Background Epigenetic changes are involved in the extinction of the B-cell gene expression program of classical Hodgkin lymphoma. However, little is known regarding epigenetic similarities between classical Hodgkin lymphoma and plasma cell myeloma cells, both of which share an extinction of the gene expression program of mature B-cells. Design and methods Global histone H3 acetylation patterns were determined in cell lines derived from classical Hodgkin lymphoma, plasma cell myeloma and B-cell lymphoma by chromatin immunoprecipitation and subsequent hybridization onto promoter tiling arrays. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL96
9 Samples

Download data: CEL, TXT

Series

Accession:: GSE28079

ID:: 200028079

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000212544.

Classical Hodgkin lymphoma shows epigenetic features of an abortive plasma cellular differentiation

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by array; Genome binding/occupancy profiling by genome tiling array

Platforms:: GPL5082 GPL96
52 Samples

Download data: BAR, BED, CEL

Series

Accession:: GSE21254

ID:: 200021254

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000212535.

Classical Hodgkin lymphoma shows epigenetic features of an abortive plasma cellular differentiation: acetyl H3 K9/14 ChIP-chip

Organism:: Homo sapiens

Type:: Genome binding/occupancy profiling by genome tiling array

Platform:: GPL5082
9 Samples

Download data: BAR, BED, CEL, TXT

Series

Accession:: GSE21253

ID:: 200021253

PubMed Full text in PMC Similar studies

Select item 2000212526.

Classical Hodgkin lymphoma shows epigenetic features of an abortive plasma cellular differentiation: expression of A/T-treated vs. untreated B-cell lines

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL96
22 Samples

Download data: CEL, TXT

Series

Accession:: GSE21252

ID:: 200021252

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000212517.

Classical Hodgkin lymphoma shows epigenetic features of an abortive plasma cellular differentiation: expression of Hodgkin vs. B-cell lines

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL96
12 Samples

Download data: CEL, TXT

Series

Accession:: GSE21251

ID:: 200021251

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000348808.

Epigenetic reprogramming in relapsed childhood ALL

(Submitter supplied) Reversing gene expression signatures in relapsed patient may restore chemosensitivity. We demonstrate that the histone deacetylase inhibitor vorinostat not only reprograms the aberrant gene expression profile of relapsed blasts but is synergistic when applied prior to chemotherapy in primary patient samples and leukemia cell lines

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL570
14 Samples

Download data: CEL

Series

Accession:: GSE34880

ID:: 200034880

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000344529.

A Multi-loop, Double-cube Microarray Design Applied to Prostate Cancer Cell Lines with Variable Sensitivity to Histone Deacetylase Inhibitors

(Submitter supplied) Implementation of a complex design for a microarray experiment on resistance mechanisms of histone deacetylase inhibitors (HDACI).

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL887
22 Samples

Download data: TXT

Series

Accession:: GSE34452

ID:: 200034452

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20005842110.

Increased Protein Processing Gene Signature in HDACi-resistant cells predicts response to proteasome inhibitors.

(Submitter supplied) Epigenetic modifying enzymes are commonly mutated in diffuse large B cell lymphoma (DLBCL). Importantly, genetics abnormalities lead to inactivation of HAT, which tilt the balance in favor of decreased protein acetylation in DLBCL cells. This suggests that protein acetylation regulation is an important factor in DLBCL pathogenesis and a potential target for therapy. We developed resistant cell lines to the histone deacetylase inhibitor (HDACi) vorinostat, in order to better define molecular mechanisms of action of HDACi in lymphoma cells. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL17077
8 Samples

Download data: TXT

Series

Accession:: GSE58421

ID:: 200058421

Select item 20016431811.

Transcriptome analysis of KM-H2 cells with different Rhodamin 123 eflux capacity

(Submitter supplied) Rhodamin 123 is a dye which can be used to detect the activity of ABC transporters. We observed that after staining of KM-H2 Hodgkin lymphoma cells with Rhodamin 123, part of the cells rapidly eliminated the dye, while another part of the cells retained the dye for a longer time. We compared the transcriptome of KM-H2 Hodgkin lymphoma cells with high Rhodamin 123 efflux capacity and KM-H2 cells with low Rhodamin 123 efflux capacity.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL23126
2 Samples

Download data: CEL, CHP

Series

Accession:: GSE164318

ID:: 200164318

PubMed Full text in PMC Similar studies

Select item 20004098812.

Gene expression profile of Hodgkin’s lymphoma cells after knock-down of PRAME

(Submitter supplied) By using high-density DNA microarrays, we analyzed the gene-expression profile of Hodgkin's lymphoma cell line L-428 after knock-down of the tumor antigen PRAME (preferentially expressed antigen in melanoma) Kewitz and Staege, submitted

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL570
2 Samples

Download data: CEL

Series

Accession:: GSE40988

ID:: 200040988

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20004767013.

Microarray analysis of derived doxorubicin resistant neuroblastoma SK-N-Be(2)C and SK-N-SH cell lines

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL10558
24 Samples

Download data

Series

Accession:: GSE47670

ID:: 200047670

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20004766914.

Genome-wide analysis of parental and wild-type SK-N-Be(2)C neuroblastoma cell lines as well as those co-treated with the histone deacetylase inhibitor SAHA

(Submitter supplied) Analysis of varied biologic pathways in neuroblastoma SK-N-Be(2)C cells grown in doxorubicin and/or SAHA. We hypothesized that SK-N-Be(2)C cells undergo a mesenchymal change through mesenchymal change resulting in a more invasive as well as drug resistant phenotype, and that the mechanism of SAHAs effect on drug resistance may be revealed through this analysis.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL10558
12 Samples

Download data: TXT

Series

Accession:: GSE47669

ID:: 200047669

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20004766815.

Genome-wide analysis of parental wild-type and derived doxorubicin resistant SK-N-SH neuroblastoma cell lines as well as those co-treated with the histone deacetylase inhibitor SAHA

(Submitter supplied) Analysis of varied biologic pathways in neuroblastoma SK-N-SH cells grown in doxorubicin and/or SAHA. The hypothesis was that SK-N-SH cells undergo a mesenchymal change through mesenchymal change resulting in a more invasive as well as drug resistant phenotype, and that the mechanism of SAHAs effect on drug resistance may be revealed through this analysis.