GEO DataSets

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Escherichia coli; Staphylococcus aureus; Sus scrofa domesticus; Bos primigenius; Streptococcus pyogenes; Pseudomonas aeruginosa; Bacillus subtilis; Salmonella enterica subsp. enterica serovar Typhimurium; Mycobacterium tuberculosis; Homo sapiens

Type:

Other

Platforms:

GPL15505 GPL15506 GPL15535

108 Samples

Download data: TXT

(Submitter supplied) Lipids comprise 70% of the myelin sheath, and autoantibodies against lipids may contribute to the demyelination that characterizes multiple sclerosis (MS). We used lipid antigen microarrays and lipid mass spectrometry to identify bona fide lipid targets of the autoimmune response in MS brain and an animal model of MS to explore the role of the identified lipids in autoimmune demyelination. We found that autoantibodies in MS target a phosphate group in phosphatidylserine and oxidized phosphatidylcholine derivatives. more...

Organism:

Bacillus subtilis; Salmonella enterica subsp. enterica serovar Typhimurium; Escherichia coli; Staphylococcus aureus; Pseudomonas aeruginosa; Mycobacterium tuberculosis; Homo sapiens; Sus scrofa domesticus; Bos primigenius; Streptococcus pyogenes

Type:

Other

Platform:

GPL15535

25 Samples

Download data: TXT

(Submitter supplied) Lipids comprise 70% of the myelin sheath, and autoantibodies against lipids may contribute to the demyelination that characterizes multiple sclerosis (MS). We used lipid antigen microarrays and lipid mass spectrometry to identify bona fide lipid targets of the autoimmune response in MS brain and an animal model of MS to explore the role of the identified lipids in autoimmune demyelination. We found that autoantibodies in MS target a phosphate group in phosphatidylserine and oxidized phosphatidylcholine derivatives. more...

Organism:

Mycobacterium tuberculosis; Homo sapiens; Pseudomonas aeruginosa; Bacillus subtilis; Streptococcus pyogenes; Escherichia coli; Staphylococcus aureus; Sus scrofa domesticus; Bos primigenius; Salmonella enterica subsp. enterica serovar Typhimurium

Type:

Other

Platform:

GPL15506

24 Samples

Download data: TXT

(Submitter supplied) Lipids comprise 70% of the myelin sheath, and autoantibodies against lipids may contribute to the demyelination that characterizes multiple sclerosis (MS). We used lipid antigen microarrays and lipid mass spectrometry to identify bona fide lipid targets of the autoimmune response in MS brain and an animal model of MS to explore the role of the identified lipids in autoimmune demyelination. We found that autoantibodies in MS target a phosphate group in phosphatidylserine and oxidized phosphatidylcholine derivatives. more...

Organism:

Escherichia coli; Staphylococcus aureus; Sus scrofa domesticus; Streptococcus pyogenes; Bos primigenius; Bacillus subtilis; Salmonella enterica subsp. enterica serovar Typhimurium; Pseudomonas aeruginosa; Mycobacterium tuberculosis; Homo sapiens

Type:

Other

Platform:

GPL15505

59 Samples

Download data: TXT

(Submitter supplied) Gene transcripts and proteins expressed during disease pathogenesis identify targets for therapy. We performed microarray analysis of histologically characterized multiple sclerosis (MS) brain lesions in comparison with control brain samples to identify differentially expressed molecules. We identified CD47 as a target of interest and studied its biology in MS and EAE.

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS4218

Platform:

GPL570

7 Samples

Download data: CEL

Analysis of histologically characterized multiple sclerosis (MS) brain lesions. MS is an inflammatory autoimmune disease which progresses to demyelination of the brain and spinal cord. Results provide insight into molecular events during MS pathogenesis.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 4 disease state, 4 other, 2 tissue sets

Platform:

GPL570

Series:

GSE38010

7 Samples

Download data: CEL