GEO DataSets

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Homo sapiens

Type:

Genome variation profiling by SNP array; Genome variation profiling by genome tiling array

Platforms:

GPL15793 GPL10150

128 Samples

Download data: CEL, TXT

(Submitter supplied) Metastatic urothelial carcinoma (UC) of the bladder is associated with multiple somatic copy number alterations (SCNAs). We evaluated SCNAs to identify predictors of poor survival in patients with metastatic UC treated with platinum chemotherapy.

Organism:

Homo sapiens

Type:

Genome variation profiling by genome tiling array

Platform:

GPL10150

94 Samples

Download data: BED, PDF, TXT

(Submitter supplied) Metastatic urothelial carcinoma (UC) of the bladder is associated with multiple somatic copy number alterations (SCNAs). We evaluated SCNAs to identify predictors of poor survival in patients with metastatic UC treated with platinum chemotherapy.

Organism:

Homo sapiens

Type:

Genome variation profiling by SNP array

Platform:

GPL15793

34 Samples

Download data: BED, CEL, PDF, TXT

(Submitter supplied) Urothelial carcinoma of the bladder is characterized by significant variability in clinical outcomes depending on stage and grade. The addition of molecular information may improve our understanding of such heterogeneity and enhance prognostic prediction. The purpose of this study was to validate and improve published prognostic signatures for high-risk bladder cancer.

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS4456

Platform:

GPL570

93 Samples

Download data: CEL, TXT

Analysis of bladder cancer specimens from a high-risk population of patients who underwent radical cystectomy (Memorial Sloan-Kettering Cancer Center cohort). Results provide insight into the prediction of survival in high-risk urothelial carcinoma of the urinary bladder.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 2 disease state, 5 specimen sets

Platform:

GPL570

Series:

GSE31684

93 Samples

Download data: CEL

(Submitter supplied) We sought to test the hypothesis that ascertainment of genome-wide copy number alterations in bladder cancer may have value for clinical management. We performed a genome wide analysis of 164 bladder cancer samples and 27 bladder cancer cell lines to identify genetic changes associated with disease characteristics. Multiplex inversion probe (MIP) analysis, a newly developed genomic technique, was used to study 80 bladder cancers to identify mutations and copy number changes. more...

Organism:

Homo sapiens

Type:

Genome variation profiling by SNP array

Platform:

GPL13270

80 Samples

Download data: CEL

(Submitter supplied) Pancreatic cancer is the fourth leading cancer-related death in United States. The clinical relevance of genomic imbalances in pancreatic cancer is uncertain. We performed array-comparative genomic hybridization (aCGH) in 44 resected pancreatic cancer specimens from a Korean cohort. We observed recurrent copy number gains were observed in chromosome 1q, 11q, 18q11.1-11.2, and 20q13.13; and losses in chromosome 2p, 9p, 10q, 14q, 15q, 18q12.2-23, 19q, 20q11.1, 21p, and 22q. more...

Organism:

Homo sapiens

Type:

Genome variation profiling by array

Platform:

GPL4093

44 Samples

Download data: TXT

(Submitter supplied) We aimed to provide a molecular description of Lynch syndrome-associated urothelial cancer in relation to molecular subtypes of sporadic bladder cancer. Whole genome mRNA expression profiles of 41 tumors and immunohistochemical stainings against FGFR3, KRT5, CCNB1, RB1, and CDKN2A (p16) of 37 tumors from Lynch syndrome patients were generated. Pathological data, microsatellite instability, anatomic location, and overall survival data was analyzed and compared with data from sporadic bladder cancer.

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL6244

41 Samples

Download data: CEL