Similar studies for GEO DataSets (Select 200046410) - GEO DataSets

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Items: 3

Select item 2000464101.

Differential gene expression in mouse kidney following 72 hours of colistin exposure by Illumina WG-6_V2 array

(Submitter supplied) Colistin sulfate (polymixin E) is an antibiotic prescribed with resurging frequency for multidrug resistant gram negative bacterial infections. It is associated with nephrotoxicity in humans in up to 33% of cases. Little is known regarding genes involved in colistin nephrotoxicity. A murine model of colistin-mediated kidney injury was developed. C57/BL6 mice were administered saline or colistin at a dose of 16mg/kg/day in 2 divided doses. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS4834
Platform:: GPL6887
12 Samples

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Series

Accession:: GSE46410

ID:: 200046410

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 48342.

Colistin effect on the kidney

Analysis of kidneys from C57BL/6J males following treatment with colistin. Colistin is an antibiotic prescribed for multidrug resistant gram negative bacterial infections. It is associated with nephrotoxicity. Results provide insight into the molecular basis of colistin nephrotoxicity.

Organism:: Mus musculus

Type:: Expression profiling by array, count, 2 agent sets

Platform:: GPL6887
Series:: GSE46410
12 Samples

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DataSet

Accession:: GDS4834

ID:: 4834

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 2001217923.

Expression data from the kidney of Sprague-Dawley rats given colistin methanesulfonate sodium

(Submitter supplied) To investigate the mechanism of nephrotoxicity, colistin methanesulfonate sodium (CMS; 25 or 50 mg/kg) was administered via intraperitoneal injection to Sprague–Dawley rats daily over 7 d. Affymetrix GeneChip microarrays indicated 894 differentially expressed genes in groups treated with CMS (ANOVA, FDR < 0.05, fold change ≥ 1.3).