Similar studies for GEO DataSets (Select 200050697) - GEO DataSets

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Items: 10

Select item 2000506971.

Gene expression of SUM159 breast cancer cell line expressing microRNA--203

(Submitter supplied) Determine the effect of miR-203 expression on the global mRNA expression in mesenchymal breast cancer cell line.

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS5348
Platform:: GPL570
6 Samples

Download data: CEL, CHP

Series

Accession:: GSE50697

ID:: 200050697

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 53482.

miR-203 overexpression effect on mesenchymal-like breast cancer cell line

Analysis of SUM159 mesenchymal-like breast cancer cells overexpressing miR-203. Result provide insight into the role of miR-203 in epithelial-mesenchymal transition and metastasis in breast cancer.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 protocol sets

Platform:: GPL570
Series:: GSE50697
6 Samples

Download data: CEL, CHP

DataSet

Accession:: GDS5348

ID:: 5348

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 2000568013.

Jagged1 regulates miRNA expression profile

(Submitter supplied) miRNA expression profiles of HMECs treated with 40mM Jagged1 (JAG1) or the control peptide for 1 day

Organism:: Homo sapiens

Type:: Other

Platform:: GPL18572
2 Samples

Download data: TXT

Series

Accession:: GSE56801

ID:: 200056801

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000585604.

TWIST1-induced microRNA-424 drives an intermediate epithelial-to-mesenchymal transition that opposes metastasis

(Submitter supplied) Using a TWIST1-inducible epithelial-to-mesenchymal transition (EMT) model in HMLE cells, miRNA changes were profiled at different time points during an active EMT.

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL18795
12 Samples

Download data: TXT

Series

Accession:: GSE58560

ID:: 200058560

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000545055.

TWIST1-induced microRNA-424 drives an intermediate epithelial-to-mesenchymal transition that opposes metastasis

(Submitter supplied) Epithelial-to-mesenchymal transition (EMT) is a dynamic process that relies on cellular plasticity; an EMT/MET axis is critical for metastatic colonization of carcinomas. Unlike epithelial programming, regulation of mesenchymal programming is not well understood in EMT. Here we describe the first microRNA that enhances exclusively mesenchymal programming. We demonstrate that microRNA-424 is up-regulated early during a TWIST1/SNAI1-induced EMT, and that it causes cells to express mesenchymal genes without affecting epithelial genes, resulting in a mixed/intermediate EMT. more...

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL11154
6 Samples

Download data: TXT

Series

Accession:: GSE54505

ID:: 200054505

PubMed Full text in PMC Similar studies Analyze with GEO2R SRA Run Selector

Select item 2000429626.

SABiosciences Human miRNA PCR array assay of normal respiratory epithelia and lung cancer cells with or without treatment of CSC

(Submitter supplied) MicroRNAs are critical mediators of stem cell pluripotency, differentiation and malignancy. Limited information exists regarding microRNA alterations that facilitate initiation and progression of human lung cancers. In this study, array techniques were used to evaluate microRNA expression in normal human respiratory epithelia and lung cancer cells cultured in the presence or absence of cigarette smoke condensate (CSC). more...

Organism:: Homo sapiens

Type:: Other

Platform:: GPL16382
8 Samples

Download data: TXT

Series

Accession:: GSE42962

ID:: 200042962

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000622307.

Expression of miR-200c in claudin-low breast cancer alters stem cell functionality, enhances chemosensitivity and reduces metastatic potential

(Submitter supplied) Claudin-low tumors are a highly aggressive breast cancer subtype with no targeted treatments and a clinically documented resistance to chemotherapy. They are significantly enriched in cancer stem cells (CSCs), which makes claudin-low tumor models particularly attractive for studying CSC behavior and developing novel approaches to minimize CSC therapy resistance. One proposed mechanism by which CSCs arise is via an epithelial-mesenchymal transition (EMT), and reversal of this process may provide a potential therapeutic approach for increasing tumor chemosensitivity. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL11383
7 Samples

Download data

Series

Accession:: GSE62230

ID:: 200062230

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000566218.

TGF-beta stimulation in ovarian cancer cells

(Submitter supplied) Genome-wide DNA methylation profiles of TGF-beta ovarian cancer cells were obtained using next generation Illumina Infinium 450k assay which includes over 450,000 GpG sites.

Organism:: Homo sapiens

Type:: Methylation profiling by genome tiling array

Platform:: GPL13534
12 Samples

Download data: TXT

Series

Accession:: GSE56621

ID:: 200056621

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2001964999.

Gene expression (GeneChip) data from scramble- and CRMP2A siRNA-treated A549 cells.

(Submitter supplied) We sought to assess how temporary loss of the microtubule-associated protein CRMP2A could affect global gene expression in the A549 lung cancer cells. We used microarrays to identify differentially regulated genes when CRMP2A is temporarily removed from A549 cells using siRNA.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL15207
2 Samples

Download data: CEL

Series

Accession:: GSE196499

ID:: 200196499

Select item 20019649410.

Gene expression (GeneChip) data from parental (wild-type) and CRMP2A KO (CRISPR) A549 cells.

(Submitter supplied) We sought to assess how permanent loss of the microtubule-associated protein CRMP2A could affect global gene expression in the A549 lung cancer cells. We used microarrays to identify differentially regulated genes when CRMP2A is permanently removed from A549 cells using CRISPR/Cas9.