GEO DataSets

(Submitter supplied) Profiling of miRNA expressions comparing standard fracture healing models with nonunion models in rats

Organism:

Mus musculus; Human alphaherpesvirus 1; Human betaherpesvirus 5; Murid betaherpesvirus 1; Human immunodeficiency virus 1; human gammaherpesvirus 4; JC polyomavirus; Human gammaherpesvirus 8; Mus musculus cytomegalovirus 2; Betapolyomavirus macacae; Homo sapiens; Murid gammaherpesvirus 4; Betapolyomavirus hominis; Rattus norvegicus; Human alphaherpesvirus 2; Merkel cell polyomavirus

Type:

Non-coding RNA profiling by array

Platform:

GPL11434

2 Samples

Download data: TXT

(Submitter supplied) The association between DM and impaired fracture healing including delayed union and nonunion has been documented in clinical and experimental settings. We examine miRNA expression specific for impaired fracture healing in diabetic rat.

Organism:

Rattus norvegicus

Type:

Non-coding RNA profiling by array

Platform:

GPL21257

4 Samples

Download data: TXT

(Submitter supplied) To further understand the molecular complexity of fracture repair, we investigated miRNA profiling during the first 14 days post fracture.

Organism:

Mus musculus

Type:

Non-coding RNA profiling by array

Platform:

GPL21265

21 Samples

Download data: TXT

(Submitter supplied) Perturbations in the expression profiles of microRNAs (miRNAs) have been reported for a variety of different cancers. Basal cell carcinoma (BCC) of the skin has not been systematically evaluated regarding differentially expressed miRNAs. Patients with BCC (n=7) were included in the study. Punch biopsies were harvested from the center of the tumors (lesional, n=7) and from sites of adjacent non-lesional skin (intraindividual control, n=7). more...

Organism:

Homo sapiens

Type:

Non-coding RNA profiling by array

Platform:

GPL15019

14 Samples

Download data: TXT

(Submitter supplied) Perturbations in microRNA (miRNA) expression profiles has been reported for cutaneous malignant melanoma (CMM). With regards to a rapidly growing number of newly discovered miRNA sequences, the availability of up-to-date miRNA expression profiles for primary cutaneous malignant melanoma (PCMM), cutaneous malignant melanoma metastases (CMMM) and benign melanocytic naevi (BMN) is limited. Patients with PCMM (n=9), CMMM (n=4) and BMN (n=8) were included in the study. more...

Organism:

Homo sapiens

Type:

Non-coding RNA profiling by array

Platform:

GPL15019

21 Samples

Download data: TXT

(Submitter supplied) A microRNA array was performed using human primary osteoblasts (hOB) obtained from trabecular bone of postmenopausal women after knee replacement due to osteoarthritis in order to determine the miRNAs expressed in these osteoblastic cells.

Organism:

Human alphaherpesvirus 2; Betapolyomavirus hominis; Homo sapiens; Macacine alphaherpesvirus 1; Merkel cell polyomavirus; Herpesvirus saimiri (strain 11); JC polyomavirus; Human immunodeficiency virus 1; Human gammaherpesvirus 8; Human alphaherpesvirus 1; Human betaherpesvirus 5; human gammaherpesvirus 4; Human betaherpesvirus 6B; Betapolyomavirus macacae

Type:

Non-coding RNA profiling by array

Platform:

GPL20999

4 Samples

Download data: TXT, XLSX

(Submitter supplied) MicroRNAs (miRNAs) are important regulators of gene expression, with documented roles in bone metabolism and osteoporosis, suggesting potential therapeutic targets. Our aim was to identify miRNAs differentially expressed in fractured vs nonfractured bones. Additionally, we performed a miRNA profiling of primary osteoblasts to assess the origin of these differentially expressed miRNAs. Total RNA was extracted from (a) fresh femoral neck trabecular bone from women undergoing hip replacement due to either osteoporotic fracture (OP group, n=6) or osteoarthritis in the absence of osteoporosis (Control group, n=6), matching the two groups by age and body mass index, and (b) primary osteoblasts obtained from knee replacement due to osteoarthritis (n=4). more...

Organism:

Human alphaherpesvirus 2; Human betaherpesvirus 6B; human gammaherpesvirus 4; Betapolyomavirus macacae; Macacine alphaherpesvirus 1; Herpesvirus saimiri (strain 11); JC polyomavirus; Human immunodeficiency virus 1; Human gammaherpesvirus 8; Merkel cell polyomavirus; Homo sapiens; Human alphaherpesvirus 1; Human betaherpesvirus 5; Betapolyomavirus hominis

Type:

Non-coding RNA profiling by array

Platform:

GPL20999

12 Samples

Download data: TXT, XLSX

(Submitter supplied) Liver is uniquely capable to repair itself after injury. Multiple molecular and biochemical processes initiated after partial hepatectomy, lead to proliferation of all cells within the liver. MicroRNAs (miRNAs) are a class of highly abundant non-coding RNA molecules that cause post-transcriptional gene repression and are involved in several biological processes including cell cycle regulation and differentiation. more...

Organism:

Rattus norvegicus; Murid gammaherpesvirus 4; Betapolyomavirus hominis; Mus musculus; Murid betaherpesvirus 1; JC polyomavirus; Human immunodeficiency virus 1; Human gammaherpesvirus 8; Homo sapiens; Human alphaherpesvirus 1; Human betaherpesvirus 5; human gammaherpesvirus 4; Betapolyomavirus macacae

Type:

Non-coding RNA profiling by array

Platform:

GPL7723

2 Samples

Download data: TXT

(Submitter supplied) MicroRNAs (miRNAs) are small, stable non-coding RNA molecules with regulatory function and marked tissue specificity that post-transcriptionally regulate gene expression, however their role in fungal keratitis remain unknown. Our purpose was to identify the miRNAs in human cornea from fungal keratitis patients and understand their key role in regulation of pathogenesis. Corneal samples from normal cadaver (n=3) and fungal keratitis (n=5) patients were pooled separately and total RNA was extracted. more...

Organism:

Homo sapiens

Type:

Non-coding RNA profiling by high throughput sequencing

Platform:

GPL15433

2 Samples

Download data: TXT

(Submitter supplied) Although cellular and molecular mechanisms during the course of bone healing have been thoroughly investigated, the regulation of gene expression by microRNA during bone regeneration is still poorly understood. We hypothesized that nonunion formation is associated with different microRNA expression patterns and that target proteins of these microRNAs are differently expressed in callus tissue of nonunions compared to physiologically healing bones. more...

Organism:

Mus musculus

Type:

Non-coding RNA profiling by array

Platform:

GPL26837

8 Samples

Download data: TXT

(Submitter supplied) Small RNA-seq was used to identify miRNAs in pupal stage Sarcophaga bullata and to assess differences in the abundance of miRNAs in developing and diapause (i.e. dormant) pupae.

Organism:

Sarcophaga bullata

Type:

Non-coding RNA profiling by high throughput sequencing

Platform:

GPL23019

6 Samples

Download data: TXT, XLS

(Submitter supplied) A microarray study about miRNA expression profiles in recurrent implantation failure patients as compare with who had got pregnancy after embryo implantation no more than three times To detect the miRNAs that may regulate endometrial receptivity by microarray study

Organism:

Homo sapiens

Type:

Non-coding RNA profiling by array

Platform:

GPL18402

12 Samples

Download data: TXT

(Submitter supplied) A study of rat femoral fracture healing in young (6 weeks old at fracture), adult (26 weeks old at fracture), and old (52 weeks old at fracture) rats. Samples were collected at time of surgery (intact controls) and at 3 days, 1 week, 2 weeks, 4 weeks, and 6 weeks after fracture. Samples were the mid third of the femoral length including the external callus, cortical bone and marrow elements. Fracture was stabilized with an intramedullary rod prior to fracture with a Bonnarens and Einhorn device. more...

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Dataset:

GDS1995

Platform:

GPL85

18 Samples

Download data: CEL

(Submitter supplied) mRNA gene expression was measured in intact female Sprague-Dawley rats at 6 (young), 26 (adult) and 52 (older) weeks of age at the time of fracture. Samples were collected at 0, 0.4, 1, 2, 4, and 6 weeks after fracture. RNA from two rats were pooled for each Affymetrix Rat U34A array. Mid-shaft, simple, transverse left femoral fractures were induced after retrograde intramedullary rod fixation with a Bonnarens and Einhorn device. more...

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Dataset:

GDS509

Platform:

GPL85

54 Samples

Download data: CEL

(Submitter supplied) Study of rat femur fracture healing in young (6 weeks old), adult (26 weeks old), and older (52 weeks old) rats with samples collected at 0 time (no fracture) and at 0.4, 1, 2, 4, and 6 weeks after fracture. RNA from two rats were pooled for each array. Keywords = rat, femur, fracture, age, time Keywords: time-course

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Platform:

GPL85

18 Samples

Download data: CEL

(Submitter supplied) mRNA gene expression was measured in rats at 6 (young), 26 (adult) and 52 (older) weeks of age at the time of fracture. Samples were collected at 0, 0.4, 1, 2, 4, and 6 weeks after fracture. RNA from two rats were pooled for each Affymetrix Rat U34A array. Keywords = rat Keywords = fracture Keywords = age Keywords = time Keywords = femur Keywords: time-course

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Platform:

GPL85

18 Samples

Download data: CEL

Analysis of healing femurs of 6, 26, and 52-week-old Sprague-Dawley females at various time points up to 6 weeks after fracture. 6, 26, and 52-week-old animals regain normal skeletal biomechanics 4 weeks, 10 weeks, and 6 months after fracture, respectively.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, count, 3 age, 2 protocol, 6 time sets

Platform:

GPL85

Series:

GSE1371

18 Samples

Download data: CEL

Temporal analysis of gene expression following femoral fracture. Female Sprague-Dawleys at 6 (young), 26 (adult) and 52 (older) weeks of age at time of fracture. Samples analyzed at 0, 3 days, 1, 2, 4, and 6 weeks after fracture.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, count, 3 age, 6 time sets

Platform:

GPL85

Series:

GSE594

36 Samples

Download data: CEL

(Submitter supplied) This study was to identify microRNAs responsible for postnatal cardiomyocyte proliferation.

Organism:

Rattus norvegicus

Type:

Non-coding RNA profiling by array

Platform:

GPL14854

8 Samples

Download data: TXT

(Submitter supplied) To investigate which miRNAs regulate the vestibular compensation after unilateral vestibular deafferentiation (UVD), we have performed microarray for miRNAs as a discovery platform. UVD induces breakdown of the activity of ipsilesional vestibular nuclei and an unbalance of activity between bilateral vestibular nuclei. Vestibular compensation is a course of rebalancing of activities of bilateral vestibular nuclei. more...

Organism:

Rattus norvegicus

Type:

Non-coding RNA profiling by array

Platform:

GPL22760

8 Samples

Download data: TXT