Similar studies for GEO DataSets (Select 200058493) - GEO DataSets

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Items: 20

Select item 2000584931.

Expression data of wild type and C-DGCR8 KO cones at different timepoints [array]

(Submitter supplied) We have analyzed gene expression in cone photoreceptors isolated from wild type and C-DGCR8 (DiGeorge Syndrome Critical Region Gene 8) KO mice at five different time points to get a mechanistic inside into the altered molecular pathways after microRNAs depletion.

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL6246
20 Samples

Download data: CEL

Series

Accession:: GSE58493

ID:: 200058493

Select item 2000585012.

MiRNAs 182 and 183 are necessary to maintain adult cone photoreceptor outer segments and visual function

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Expression profiling by array; Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing

Platforms:: GPL6246 GPL13112
42 Samples

Download data: CEL, TXT

Series

Accession:: GSE58501

ID:: 200058501

Select item 2000585003.

MicroRNA expression profile in mouse cone photoreceptors at P60 [miRNA-seq]

(Submitter supplied) The outer segments of cones serve as light detectors for daylight color vision, and their dysfunction leads to human blindness conditions. We show that the cone-specific disruption of DiGeorge Syndrome Critical Region Gene 8 (DGCR8) in adult mice led to the loss of miRNAs and the loss of outer segments, resulting in photoreceptors with significantly reduced light responses. Using next-generation sequencing of RNA from isolated wild type P60 cones, we determine the most highly expressed miRNAs as candidates for controlling outer segment maintenance. more...

Organism:: Mus musculus

Type:: Non-coding RNA profiling by high throughput sequencing

Platform:: GPL13112
2 Samples

Download data: TXT

Series

Accession:: GSE58500

ID:: 200058500

PubMed Similar studies SRA Run Selector

Select item 2000584984.

Expression data of wild type and C-DGCR8 KO cones at different timepoints [RNA-seq]

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing

Platform:: GPL13112
20 Samples

Download data: TXT

Series

Accession:: GSE58498

ID:: 200058498

PubMed Similar studies SRA Run Selector

Select item 2001065915.

Next Generation Sequencing Facilitates Quantitative Analysis of Wild Type and miR-211-/- Whole Eye Transcriptomes

(Submitter supplied) Purpose: Next-generation sequencing (NGS) has revolutionized systems-based analysis of cellular pathways. The goals of this study are to compare NGS transcriptome profiling (RNA-seq) from whole eye, after removal of the lens and cornea from 1-2 month old miR-211-/- mice and compare it with wt mice Methods: Whole eye (after removal of the lens and cornea) mRNA profiles of 1-2 month old wild-type (WT) and neural miR-211-/-mice were generated by deep sequencing, in multiple biological replicates, five for WT and six for miR-211-/- animals, using Illumina GAIIx. more...

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing

Platform:: GPL15103
11 Samples

Download data: TXT

Series

Accession:: GSE106591

ID:: 200106591

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2000958526.

Gene expression profiles in retinas from miRNA183/182/96 cluster knockout mice versus wild type controls by RNA-seq

(Submitter supplied) Retinas from various developmental stages at postnatal p5, p11, and p27 from miRNA183/182/96 cluster knockout mice versus wild type controls were used to prepare total RNA for RNA-sequencing.

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing

Platform:: GPL13112
6 Samples

Download data: DIFF

Series

Accession:: GSE95852

ID:: 200095852

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2000849327.

RNA-Seq of tissues from Rat eye and retina samples

(Submitter supplied) We report RNA-Seq experiments of eye and retinal tissues from Rattus Norvegicus

Organism:: Rattus norvegicus

Type:: Expression profiling by high throughput sequencing

Platform:: GPL10669
4 Samples

Download data: TXT

Series

Accession:: GSE84932

ID:: 200084932

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2000849318.

RNA-Seq of eye tissues from Ground Squirrel eye and retina samples

(Submitter supplied) We report RNA-Seq experiments of eye and retinal tissues from Ground Squirrel (Ictidomys tridecemlineatus)

Organism:: Ictidomys tridecemlineatus

Type:: Expression profiling by high throughput sequencing

Platform:: GPL22249
5 Samples

Download data: TXT

Series

Accession:: GSE84931

ID:: 200084931

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2000849309.

RNA-Seq of retinal tissue from a Human Eye

(Submitter supplied) We report RNA-Seq experiments of retinal tissue from Homo Sapiens

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL10999
2 Samples

Download data: TXT

Series

Accession:: GSE84930

ID:: 200084930

PubMed Full text in PMC Similar studies Analyze with GEO2R SRA Run Selector

Select item 20008492910.

RNA-Seq of eye tissues from Monkey eye and retina samples

(Submitter supplied) We report RNA-Seq experiments of eye and retinal tissues from different ocular compartments in the Monkey

Organism:: Macaca fascicularis

Type:: Expression profiling by high throughput sequencing

Platform:: GPL17720
15 Samples

Download data: TXT

Series

Accession:: GSE84929

ID:: 200084929

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 20008492811.

RNA-Seq of eye tissue from Nile rat eye samples

(Submitter supplied) We report RNA-Seq experiments of eye tissues from Nile rat (Arivacanthis niloticus)

Organism:: Arvicanthis niloticus

Type:: Expression profiling by high throughput sequencing

Platform:: GPL22248
5 Samples

Download data: TXT

Series

Accession:: GSE84928

ID:: 200084928

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 20008492712.

RNA-Seq of tissues from Mouse eye and retina samples

(Submitter supplied) We report RNA-Seq experiments of eye and retinal tissues from WT and RHO KO mice

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing

Platform:: GPL11002
9 Samples

Download data: TXT

Series

Accession:: GSE84927

ID:: 200084927

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Select item 20004897413.

RNA-Seq of eye tissues from C57BL/6J background mice at 1.5 h and 9.0 h after light onset

(Submitter supplied) We report RNA-Seq experiments of whole eye tissues from C57BL/6J background mice at 1.5 h and 9.0 h after light onset to better understand photoreceptor phagocytosis

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing

Platform:: GPL11002
6 Samples

Download data: TXT

Series

Accession:: GSE48974

ID:: 200048974

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Select item 20003835914.

RNA-Seq of eye tissues from A/J, BALB/c, and C57BL/6 background mice

(Submitter supplied) We report RNA-Seq experiments of whole eye tissues from A/J, BALB/c, and C57BL/6 background mice.

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing

Platform:: GPL11002
9 Samples

Download data: TXT

Series

Accession:: GSE38359

ID:: 200038359

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Select item 20002975215.

RNA-Seq of mouse eye and retina tissues from wild type and Nrl transcription factor knockout mice

(Submitter supplied) The initial aim of this work was to understand the pathophysiology of Enhanced S-cone Syndrome (ESCS) that leads to retinal degeneration. Although ESCS was identified in humans decades ago and since then the causative genes have been elucidated, our understanding of the accompanying retinal degeneration is still poorly understood. Knockout of the Nrl transcription factor in mice produces a retina overpopulated with S-cone like photoreceptors along with absence of rod photoreceptors and recapitulates many of the phenotypic features seen in human ESCS patients. more...

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing

Platform:: GPL11002
4 Samples

Download data: TXT

Series

Accession:: GSE29752

ID:: 200029752

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Select item 20009753616.

RNA sequencing and ATAC sequencing of developing cone photoreceptors

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL17021
48 Samples

Download data

Series

Accession:: GSE97536

ID:: 200097536

PubMed Full text in PMC Similar studies

Select item 20009753517.

ATAC sequencing of developing cone photoreceptors

(Submitter supplied) We determined the accessible genome of postmitotic cone photoreceptors in the central region of the mouse retina on postnatal days P3, P6, and P10. At eachtimepoint we isolated GFP-labeled cells from three different Chrnb4-GFP mice (biological triplicates) using fluorescence-activated cell sorting. We then acquired reads of regions of accessible DNA of the sorted cones using ATAC sequencing. Our data set contained 9 samples.

Organism:: Mus musculus

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL17021
9 Samples

Download data: BED, CSV

Series

Accession:: GSE97535

ID:: 200097535

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Select item 20009753418.

RNA sequencing of developing cone photoreceptors

(Submitter supplied) We determined the transcriptomes of postmitotic cone photoreceptors in the central region of the mouse retina every day between birth (P0) and eye opening (P12). At each postnatal day we isolated GFP-labeled cells from three different Chrnb4-GFP mice (biological triplicates) using fluorescence-activated cell sorting. We then acquired the transcriptomes of the sorted cones using next generation RNA sequencing. more...

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing

Platform:: GPL17021
39 Samples

Download data: CSV

Series

Accession:: GSE97534

ID:: 200097534

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Select item 20018078119.

Regulation of retina microexons by srrm3 in zebrafish and by SRRM3, SRRM4 and MSI1 in human cell lines

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Danio rerio; Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platforms:: GPL16791 GPL18413
15 Samples

Download data: TXT

Series

Accession:: GSE180781

ID:: 200180781

PubMed Full text in PMC Similar studies

Select item 20018077920.

Regulation of retina microexons by SRRM3, SRRM4 and MSI1 in human cell lines

(Submitter supplied) To investigate the role of MSI1, SRRM3 and SRRM4 as a regulator of retina microexons (RetMICs) in vitro in humans, we have ectopically expressed these genes in HEK293 cells and performed RNA-seq.