Similar studies for GEO DataSets (Select 200068743) - GEO DataSets

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Items: 20

Select item 2000687431.

Gene expression signatures in GIST-T1 cells transfected with miR-34a and miR-335 mimic molecules

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL16699
8 Samples

Download data: TXT

Series

Accession:: GSE68743

ID:: 200068743

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000687422.

Gene expression signatures in GIST-T1 cells transfected with a miR-335 mimic molecule

(Submitter supplied) To clarify the effect of miRNAs, we carried out a gene expression microarray analysis using GIST-T1 cells transfected with a miR-335 mimic or a negative control. We found that 1,095 probe sets (853 unique genes) were downregulated (>1.5-fold) by ectopic miR-335 expression.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL16699
4 Samples

Download data: TXT

Series

Accession:: GSE68742

ID:: 200068742

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000687403.

Gene expression signatures in GIST-T1 cells transfected with a miR-34a mimic molecule

(Submitter supplied) To clarify the effect of miRNAs, we carried out a gene expression microarray analysis using GIST-T1 cells transfected with a miR-34a mimic or a negative control. We found that 2,621 probe sets (1,933 unique genes) were downregulated (>1.5-fold) by ectopic miR-34a expression, including PDGFRA gene which was previously reported as a miR-34a target gene.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL16699
4 Samples

Download data: TXT

Series

Accession:: GSE68740

ID:: 200068740

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000417604.

Gene expression signatures in a human bladder cancer cell line SW780 transfected with miR-137 precursor molecule

(Submitter supplied) To clarify the effect of miRNAs, we carried out a gene expression microarray analysis of SW780 cells transfected with a miR-137 precursor or a negative control. We found that 1,326 probe sets (1,016 unique genes) were downregulated (>2-fold) by ectopic miR-137 expression, including the previously reported miR-137 target genes CDK6, CDC42 and AURKA. Moreover, Gene Ontology analysis revealed that genes related to the cell cycle were significantly enriched among the affected genes.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL13607
2 Samples

Download data: TXT

Series

Accession:: GSE41760

ID:: 200041760

Select item 2000896735.

Transcriptome analysis of GIST430 and GIST882 cells transfected with nontargeting microRNA or with miR-494

(Submitter supplied) Gene expression microarry by using GIST430 and GIST882 cells with or without miR-494 treatment

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL10558
12 Samples

Download data: TXT

Series

Accession:: GSE89673

ID:: 200089673

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000733466.

Function annotation and clinical implications of KIT mutation and overexpression associated microRNAs in gastrointestinal stromal tumours

(Submitter supplied) Activating mutation of KIT is well known as a key molecular event for the development of gastrointestinal stromal tumors(GISTs). Dysregulation of microRNAs(miRNA) might elucidate KIT mutation, KIT overexpression and the resulting tumorigenesis in GIST. Herein we identified miRNA expression profiles that associated with KIT mutation and KIT overexpression in GIST by miRNA microarrays and Real-time PCR in GISTs. more...

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL20948
10 Samples

Download data: TXT

Series

Accession:: GSE73346

ID:: 200073346

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000162397.

Genes regulated by miR-181c

(Submitter supplied) We found frequently down-regulation of microRNA-181c in human gastric cancer cases. To identify the potential target of miR-181c, we introduced miR-181c into a gastric cancer cell line KATO-III　and analyzed significant changes of gene expression which was induced after introducing miR-181c. Keywords: dose response

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL6480
1 Sample

Download data: TXT

Series

Accession:: GSE16239

ID:: 200016239

Select item 2000160068.

MicroRNAs regulated by DAC

(Submitter supplied) Aberrant expression of microRNA (miRNA) has been reported in various cancers. To clarify the role of miRNA in gastric carcinogenesis, we performed miRNA microarray analysis and investigated expressional changes of miRNAs in a 5-aza-2'-deoxycytidine (DAC)-treated gastric cancer cell line, KATO-ІІІ.

Organism:: Homo sapiens; Mus musculus; Rattus norvegicus

Type:: Non-coding RNA profiling by array

Platform:: GPL5106
2 Samples

Download data: TIFF, TXT

Series

Accession:: GSE16006

ID:: 200016006

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000104559.

Genes regulated by miR-34b/c and DAC

(Submitter supplied) We found frequent epigenetic silencing of microRNA-34b/c in human colorectal cancer. Introduction of miR-34b/c into a colorectal cancer cell line induced significant changes in gene expression profile. We also found overlap between the genes downregulated by miR-34b/c and those downregulated by DAC. Keywords: dose response

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL4133
5 Samples

Download data: TXT

Series

Accession:: GSE10455

ID:: 200010455

Select item 20004590110.

Small RNA expression signatures of gastrointestinal stromal tumors: associations to imatinib resistance and patient outcome

(Submitter supplied) We performed miRNA expression profiling in a series of fresh-frozen neoadjuvantly imatinib treated gastrointestinal stromal tumors (GIST), using a microarray approach. Significant differentially expressed miRNAs among imatinib-resistant and imatinib-sensitive groups were identified using SAM analysis.

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL10656
17 Samples

Download data: TXT

Series

Accession:: GSE45901

ID:: 200045901

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20005385011.

miRNA expression profiling of Human Myeloma Cell Lines Pre- and Post- 5'azacytidine Treatment

(Submitter supplied) We performed genome-wide miRNA expression profiling (MEP) of a panel of four human Myeloma cell lines treated with 5'azacytidine compared to control (DMSO treatment), with the objective of unmasking miRNAs silenced by DNA hypermethylation.

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL16770
8 Samples

Download data: TXT

Series

Accession:: GSE53850

ID:: 200053850

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20003206412.

Gene expression signatures in GIST-T1 cells transfected with siRNA targeting HOTAIR

(Submitter supplied) To analyze the effect of HOTAIR depletion in a gastrointestinal stromal tumor (GIST) cells, RNAi-mediated knockdown of HOTAIR was carried out using GIST-T1 cells. Gene expression microarray analysis revealed that a number of reported HOTAIR target genes were upregulated by knockdown of HOTAIR. Moreover, we found that 1424 genes were upregulated by siHOT (>2-fold), and Gene Ontology analysis revealed enrichment of genes related to “nucleus”, “chromosome” and “membrane-bounded organelle.”

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL13607
2 Samples

Download data: TXT

Series

Accession:: GSE32064

ID:: 200032064

Select item 20003180213.

Gene expression signatures in gastrointestinal stromal tumors (GISTs)

(Submitter supplied) To analyze the gene expression signatures in gastrointestinal stromal tumors (GISTs), a series of 14 GIST specimens were analyzed using Agilent Whole Human Genome Microarray (4x44K, G4112F).

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL4133
14 Samples

Download data: TXT

Series

Accession:: GSE31802

ID:: 200031802

Select item 20003174114.

miRNA expression signatures in gastrointestinal stromal tumors (GISTs)

(Submitter supplied) To clarify the microRNA (miRNA) expression signatures in gastrointestinal stromal tumors (GISTs), a series of 32 GIST specimens were analyzed using Agilent miRNA microarray V3. Unsupervised hierarchical clustering revealed that GISTs can be categorized into 2 groups according to the expression of a miRNA cluster encoded on chromosome 14q32.31.

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL10406
32 Samples

Download data: TXT

Series

Accession:: GSE31741

ID:: 200031741

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20007657615.

Comparison of miRNA expression in HT29-tsp53 cells cultured at the permissive and restrictive temperatures

(Submitter supplied) The p53 tumour suppressor is a transcription factor that can regulate the expression of numerous genes encoding either proteins or microRNAs (miRNAs). The predominant outcomes of a typical p53 response are the initiation of apoptotic cascades and the activation of cell cycle checkpoints. HT29-tsp53 cells express a temperature sensitive variant of p53 and in the absence of exogenous DNA damage, these cells preferentially undergo G1 phase cell cycle arrest at the permissive temperature that correlates with increased expression of the cyclin-dependent kinase inhibitor p21WAF1. more...

Organism:: Homo sapiens; synthetic construct

Type:: Non-coding RNA profiling by array

Platform:: GPL8786
6 Samples

Download data: CEL

Series

Accession:: GSE76576

ID:: 200076576

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20008561316.

Gene expression signatures in GIST-T1 cells transfected with a miR-186 inhibitor molecule

(Submitter supplied) To clarify the role of miR-186 in GIST, we carried out a gene expression microarray analysis using GIST-T1 cells transfected with a miR-186 inhibitor or a negative control. We found that 253 probe sets (229 unique genes) were upregulated (>1.5-fold) by inhibition of miR-186 in GIST-T1 cells.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL16699
4 Samples

Download data: TXT

Series

Accession:: GSE85613

ID:: 200085613

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20008905117.

MiRNA Profiling of Gastrointestinal Stromal Tumors by Next Generation Sequencing

(Submitter supplied) Gastrointestinal stromal tumors (GISTs) have an impaired gene expression. As microRNAs (miRNAs) are involved in post-transcriptional regulation of gene expression we performed the first high-throughput miRNA profiling of 15 paired GIST formalin-fixed and paraffin-embedded samples (tumor and adjacent normal tissue) using small RNA sequencing approach.

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by high throughput sequencing

Platform:: GPL16791
30 Samples

Download data: TXT

Series

Accession:: GSE89051

ID:: 200089051

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 20002842518.

Modulation of the osteosarcoma expression phenotype by miRNAs

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by array; Expression profiling by array

Platforms:: GPL13376 GPL8227
46 Samples

Download data: TXT

Series

Accession:: GSE28425

ID:: 200028425

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20002842419.

Modulation of the osteosarcoma expression phenotype by miRNAs [Illumina]

(Submitter supplied) Background: Osteosarcomas are the most common primary malignant tumors of bone and show multiple and complex genomic aberrations. miRNAs are non-coding RNAs capable of regulating gene expression at the post transcriptional level, and miRNAs and their target genes may represent novel therapeutic targets or biomarkers for osteosarcoma. In order to investigate the involvement of miRNAs in osteosarcoma development, global microarray analyses of a panel of 19 human osteosarcoma cell lines was performed. more...