Similar studies for GEO DataSets (Select 200072322) - GEO DataSets

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Items: 14

Select item 2000723221.

Identifying molecular mechanisms of neural crest (NC) EMT and cell migration

(Submitter supplied) Purpose: To identify differntially expressed transcripts in TP-0903 treated embryos that impair cranila NC EMT and cell migration in zebrafish embryos Methods: zebrafish embryos treated at 13 hpf with 5-7uM TP-0903 and DMSO for 1-, 4- and 8-hrs at 28°C. 35 embryos were collected for each treatment. Results: TP-0903 increases expression of several retinoic acid target genes including genes from within the retinoid pathway Conclusions: TP-0903 causes a direct increase in RA signaling that impairs cranial NC EMT and cell migration in zebrafihs embryos

Organism:: Danio rerio

Type:: Expression profiling by high throughput sequencing

Platforms:: GPL14875 GPL18413
24 Samples

Download data: TXT

Series

Accession:: GSE72322

ID:: 200072322

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2001681792.

A single-cell transcriptomic analysis of cranial neural crest development reveals timing of lineage decisions and novel regulators

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Danio rerio

Type:: Expression profiling by high throughput sequencing

Platforms:: GPL18413 GPL24995
13 Samples

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Series

Accession:: GSE168179

ID:: 200168179

PubMed Full text in PMC Similar studies

Select item 2001681333.

scRNA-seq timeline of first pharyngeal arch migratory stream in zebrafish

(Submitter supplied) We have performed single-cell RNA-seq of cranial NC cells in zebrafish over several stages during their migration

Organism:: Danio rerio

Type:: Expression profiling by high throughput sequencing

Platform:: GPL18413
7 Samples

Download data: CSV

Series

Accession:: GSE168133

ID:: 200168133

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Select item 2001681314.

Bulk RNA-seq comparing expression profiles between neural crest cells experiencing high and low levels of Wnt signaling

(Submitter supplied) The purpose of this study was to obtain an unbiased list of wnt-regulated genes in zebrafish neural crest.

Organism:: Danio rerio

Type:: Expression profiling by high throughput sequencing

Platform:: GPL24995
6 Samples

Download data: TXT

Series

Accession:: GSE168131

ID:: 200168131

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2001263325.

The transcriptional repressor SNAI2 impairs neuroblastoma differentiation and inhibits response to retinoic acid therapy

(Submitter supplied) Analyses of the effect of CRISPR/CAS9 mediated knock out of the EMT-transcription factor SNAI2 on the mRNA expression profile of human neuroblastoma SH-SY5Y cells to identify genes that are differentially expressed upon loss of SNAI2. Results provide insight into genes that are repressed by SNAI2 in neuroblastoma cells under normal culture conditions, where loss of SNAI2 enhances the expression of genes involved in biological processes such as neuron development and neuron differentiation.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL20301
9 Samples

Download data: TXT

Series

Accession:: GSE126332

ID:: 200126332

Select item 2000993826.

Zebrafish zic2 controls formation of periocular neural crest and choroid fissure morphogenesis

(Submitter supplied) RNA-seq transcriptome analysis identified an early requirement for zic2 in periocular neural crest as an activator of alx1, a transcription factor with essential roles in craniofacial and ocular morphogenesis in human and zebrafish

Organism:: Danio rerio

Type:: Expression profiling by high throughput sequencing

Platform:: GPL18413
9 Samples

Download data: TXT

Series

Accession:: GSE99382

ID:: 200099382

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Select item 2001638267.

The alx3 gene functions to regulate skeletal cell differentiation timing during zebrafish neurocranium development.

(Submitter supplied) During craniofacial development, different populations of cartilage and bone forming cells develop in precise locations in the head. Most of these cells are derived from pluripotent cranial neural crest cells. The mechanisms that divide neural crest cells into distinct populations are not fully understood. Here we use single-cell RNA sequencing to transcriptomically define different populations of cranial neural crest cells. more...

Organism:: Danio rerio

Type:: Expression profiling by high throughput sequencing

Platform:: GPL24995
1 Sample

Download data: CSV

Series

Accession:: GSE163826

ID:: 200163826

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Select item 2000245298.

Expression analysis of transgenic embryos carrying the mitf-BRAFV600E allele in the presence or absence of p53 function

(Submitter supplied) Investigation of expression differences between melanomas harvested from MiniCoopR-GFP versus MiniCoopR-SETDB1 transgenic zebrafish The embryos described in this study are further analyzed in a manuscript submitted for publication by White, et al.

Organism:: Danio rerio

Type:: Expression profiling by array

Platform:: GPL1319
12 Samples

Download data: CEL

Series

Accession:: GSE24529

ID:: 200024529

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Select item 2000245289.

Expression analysis of zebrafish melanoma and skin from the mitf-BRAFV600E;p53-/- line

(Submitter supplied) Investigation of expression differences between skin and melanomas from a transgenic BRAFV600E zebrafish model of melanoma The embryos described in this study are further analyzed in a manuscript submitted for publication by White, et al.

Organism:: Danio rerio

Type:: Expression profiling by array

Platform:: GPL1319
15 Samples

Download data: CEL

Series

Accession:: GSE24528

ID:: 200024528

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Select item 20002452710.

Expression analysis of 24hpf zebrafish embryos treated with Leflunomide 6.5uM

(Submitter supplied) Identification of genes differentially regulated after treatment of zebrafish embryos from 50% epiboly to 24hpf with 6.5uM leflunomide

Organism:: Danio rerio

Type:: Expression profiling by array

Platform:: GPL1319
6 Samples

Download data: CEL

Series

Accession:: GSE24527

ID:: 200024527

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Select item 20002452611.

A375 melanoma cells treated with leflunomide 25uM

(Submitter supplied) Human A375 melanoma cells were treated with leflunomide 25uM for 3 days, then RNA harvested

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL6884
6 Samples

Download data: TXT

Series

Accession:: GSE24526

ID:: 200024526

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Select item 20012808012.

RNA helicase DDX21 mediates nucleotide stress responses (ChIP-Seq)

(Submitter supplied) The RNA helicase DDX21 acts as trancriptional sensor for nucleotide lowering

Organism:: Homo sapiens

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL16791
9 Samples

Download data: NARROWPEAK

Series

Accession:: GSE128080

ID:: 200128080

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 20016835113.

Single cell RNA-seq of E8.5 mouse embryonic craniofacial tissues

(Submitter supplied) The craniofacial region encompassing rhombomere 2 and adjacent putative BA1 together with all more anterior tissues was collected from E8.5 mouse embryos, processed and analyzed by 10X Genomics Chromium scRNA-seq

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing

Platform:: GPL24247
2 Samples

Download data: TXT

Series

Accession:: GSE168351

ID:: 200168351

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 20016260414.

Identification of Snai1b targets in zebrafish heart by transcriptomic analysis

(Submitter supplied) Purpose: identifying, with RNA-seq, genes targets of Snai1b during zebrafish cardiac development. Results: we identified several differential expressed genes, in particular cytoskeletal genes. In particular, the intermediate filament gene desmin b is upregulated.