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Expression data in muscle cells (myotubes) of motor neuron disorders (ALS, SBMA, SMA-IV) and healthy controls
PubMed Full text in PMC Similar studies Analyze with GEO2R
Micro-RNAs secreted through astrocyte-derived extracellular vesicles cause neuronal network degeneration in C9orf72 ALS
Exon Level Expression Profiling: a Novel Unbiased Transcriptome
scRNAseq of human iPSC-derived motor neurons from control and ALS patients.
PubMed Full text in PMC Similar studies SRA Run Selector
FUS-ALS hiPSC-derived astrocytes impair human motor units through both gain-of-toxicity and loss-of-support mechanisms
Human iPSC-derived astrocytes from ALS patients with mutated C9ORF72 show increased oxidative stress and neurotoxicity
Microglia influence neurofilament deposition in ALS iPSC-derived motor neurons
iPSC derived motor neuron cultures from C9ORF72 carriers
PubMed Full text in PMC Similar studies Analyze with GEO2RSRA Run Selector
Progressive motor neuron pathology and the role of astrocytes in a human stem cell model of VCP-related ALS [terminally differentiated iPSC-derived astrocytes]
Post-transcriptional remodelling is temporally deregulated during motor neurogenesis in human ALS models
PubMed Full text in PMC Similar studies
Progressive motor neuron pathology and the role of astrocytes in a human stem cell model of VCP-related ALS
Exon array analysis of control vs. FALS MPC
A regulatory circuitry between the Gria2 mRNA and miR-409/miR-495 is altered in mESC-derived motor neurons carrying an ALS-associated FUS mutation
Comparison of translational profiles in Motor Neurons (CHAT), to all neurons (Snap25) in the spinal cord.
Time-series proteomic analysis of body fluid extracellular vesicles in amyotrophic lateral sclerosis
Ropinirole hydrochloride identified by iPSC drug discovery for amyotrophic lateral sclerosis: a single-centered, randomized, double-blind, placebo-controlled phase 1/2a trial
Extracellular vesicles in serum and central nervous system tissues contain microRNA signatures in sporadic amyotrophic lateral sclerosis
Comparison of the whole transcriptomes between ALS-mutant and Healthy control motor neurons
Longitudinal and transversal comparison of iPSC-derived ALS_C9orf72 and healthy motor neurons at DIV21 and DIV42
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