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Links from GEO DataSets

Items: 3

1.

Gene expression profiling of blood of Ebola virus disease survivors and Healthy donors by Next Generation Sequencing

(Submitter supplied) Clinical follow-up of Ebola virus disease (EVD) survivors revealed a persistence of clinical symptoms and higher risk of mortality. Long-term analyses of the immune and inflammatory profiles of EVD survivors are currently lacking. Here, we evaluate gene expression profiles in 26 Guinean Ebola virus disease survivors (EBOV_S) and 33 Healthy donnors (HD). We show a persistent increase of several biomarkers of inflammation, immune activation and gut tissue damage in EBOV_S compared to healthy donors living in the same area. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL16791
59 Samples
Download data: TXT
2.

Next generation sequencing reveals a controlled immune response to Zaire Ebola virus challenge in cynomolgus macaques immunized with VSVΔG/ZEBOVgp

(Submitter supplied) RNA deep sequencing analysis was perfromed on PBMCs obtained from cynomolgus macaques (CMs) prior to and after immunization with VSV carrying ZEBOVgp (VSVΔG/ZEBOVgp) and at multiple points after ZEBOV challenge
Organism:
Macaca fascicularis
Type:
Expression profiling by high throughput sequencing
Platform:
GPL17720
30 Samples
Download data: TXT
Series
Accession:
GSE64538
ID:
200064538
3.

Immune parameters and outcome during Ebola virus disease

(Submitter supplied) Immune patterns in Ebola patients were characterized depending on the outcome of the illness. Non-healthy controls were compared to Ebola patients to define the specificity of the immune response against Ebola virus infection.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL16686
59 Samples
Download data: CEL
Series
Accession:
GSE122692
ID:
200122692
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