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Links from GEO DataSets

Items: 11

1.

Identification and Functional Analysis of MYEOV, KCNN4, S100A16 and DDX60L in Pancreatic Ductal Adenocarcinoma

(Submitter supplied) siRNA of MYEOV, KCNN4, S100A16 and DDX60L treated MiaPaCa2 and PANC-1 cells were used for RNA-seq to identify the transcriptomic alterations.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL11154
30 Samples
Download data: XLSX
2.

Identification and Functional Analysis of Novel Oncogenes in Pancreatic Ductal Adenocarcinoma

(Submitter supplied) For identifying the specific expressed genes in PDAC, we constructed sequencing libraries from polyadenylated-RNA extracted from 6 PDAC specimens and 6 non-tumor adjacent tissues.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL11154
12 Samples
Download data: CSV
3.

microRNA expression changes after knocking out MYEOV in two human pancreatic cancer cell lines

(Submitter supplied) Pancreatic cancer (PC) remains a highly lethal malignancy worldwide. As metastasis and malignant proliferation are primarily responsible for poor clinical outcomes of PC, it is imminent to dig out the pivotal gene involved in the process as well as its underlying molecular mechanism. In this study, through analysis of TCGA and GTEx data, we found that the expression level of MYEOV was obviously increased in carcinoma tissues relative to healthy ones and associated with poor survival in PC patients. more...
Organism:
Homo sapiens
Type:
Non-coding RNA profiling by high throughput sequencing
Platform:
GPL11154
12 Samples
Download data: TXT
Series
Accession:
GSE143828
ID:
200143828
4.

Global mRNA/LncRNA expression analysis of pancreatic tumors causing type3C Diabetes Mellitus

(Submitter supplied) Pancreatic tumors with small size can cause type3C Diabetes Mellitus (PCA-DM) but the mechanism is unknown. In this study we aimed at revealing the mRNA and long noncoding RNA (LncRNA) expression patterns of pancreatic tumors that triggered PCA-DM. Four pancreatic tumors from patients with PCA-DM (A1-A4), four pancreatic tumors from patients without PCA-DM (B1-B4), and four pancreatic tissues from patients with pancreatitis were individually profiled with Agilent microarrays(Arraystar Human LncRNA Array v3.0).
Organism:
Homo sapiens
Type:
Expression profiling by array; Non-coding RNA profiling by array
Platform:
GPL16956
12 Samples
Download data: TXT
Series
Accession:
GSE61166
ID:
200061166
5.

Differentially expressed genes after miRNA or siRNA transfection in human cancer cell lines (SK-MES, MDA-MB-231, MKN and 786-O)

(Submitter supplied) To identify differentially expressed genes by anti cancer treatments (microRNAs or siRNAs) in human cancer, several cell lines (lung cancer, breast cancer, gastric cancer and renal cancer) were subjected to Agilent whole genome microarrays.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL20844
8 Samples
Download data: TXT
Series
Accession:
GSE113066
ID:
200113066
6.

Expression data from pancreatic ductal adenocarcinoma

(Submitter supplied) Three PDAC tissue samples and their matched adjacent non-tumor samples were obtained and were used for microarray assay.
Organism:
Homo sapiens
Type:
Non-coding RNA profiling by array; Expression profiling by array
Platform:
GPL16956
6 Samples
Download data: TXT
Series
Accession:
GSE89139
ID:
200089139
7.

Differentially expressed genes after miRNA or siRNA transfection in human cancer cell lines (A-498, 786-O, A549, TE-8, PANC-1, SW1990, PC3 and PC3M)

(Submitter supplied) To identify differentially expressed genes by anti cancer treatments (microRNAs or siRNAs) in human cancer, several cell lines ( renal cell carcinoma, lung adenocarcinoma, esophageal, pancreatic and prostate cancer) were subjected to Agilent whole genome microarrays.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL20844
16 Samples
Download data: TXT
Series
Accession:
GSE93290
ID:
200093290
8.

circNFIB suppresses lymphatic metastasis of pancreatic cancer

(Submitter supplied) Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal malignany and currently the fourth leading cause of cancer related death worldwide. Circular RNAs (circRNAs) are a kind of novel noncoding RNA with a covalently circular structure arise from the non-canonical splicing of precursor-mRNA(pre-mRNA). To identify circRNAs involved in the progression of PDAC, next-generation sequencing (NGS) was performed in five paired PDAC and normal adjacent tissues. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing
Platform:
GPL20795
10 Samples
Download data: TXT
9.

Prognostic relevance of molecular subtypes and master regulators in pancreatic ductal adenocarcinoma

(Submitter supplied) To evaluate the prognostic relevance of molecular subtypes and key transcription factors in pancreatic ductal adenocarcinoma (PDAC), we performed gene expression analysis of whole-tumor tissue obtained from 118 surgically resected PDAC and 13 control samples.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL13667
131 Samples
Download data: CEL
Series
Accession:
GSE62165
ID:
200062165
10.

Deeper insight into Pancreatic Ductal Adenocarcinoma (PDAC) survival heterogeneity using integrative analyses of individual and global transcriptome based networks

(Submitter supplied) Purpose: The goals of this study are to delineate genes when comparing long-term (LT) and short-term (ST) PDAC survivors, and to exploit the merits of extensive integrative individual- and group-based transcriptome profiling. Method: Using a discovery cohort of 19 PDAC patients, we first performed differential gene expression (DGE) analysis comparing LT to ST PDAC groups. Second, we adopted unsupervised systems biology approaches to obtain meaningful gene modules showing associations to clinical features. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL18573
19 Samples
Download data: TXT
11.

A single-cell atlas of the tumor, stromal and immune microenvironments in pancreatic cancer liver metastasis

(Submitter supplied) Pancreatic ductal adenocarcinoma (PDAC) remains one of the most aggressive and lethal malignant tumors all over the world, with a 5-year survival rate of less than 10%1,2. Usually diagnosed at an advanced stage, PDAC is highly resistant to current therapies, partly due to an extremely high rate of distant metastasis (>80%) at first diagnosis. The liver is the most frequent site of distant metastases for PDAC. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL18573
8 Samples
Download data: MTX, TSV
Series
Accession:
GSE197177
ID:
200197177
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