Similar studies for GEO DataSets (Select 200183134) - GEO DataSets

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Items: 5

Select item 2001831341.

Transcriptomic profiling of Pityriasis Rubra Pilaris (PRP) and Psoriasis

(Submitter supplied) The microarray experiment was employed to evaluate the gene expressions in skin lesions of PRP and psoriasis.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL30572
35 Samples

Download data: CEL

Series

Accession:: GSE183134

ID:: 200183134

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000718292.

Transgenic overexpression of Pla2g2f at a level relevant to skin pathology display alopecia and psoriasis-like epidermal hyperplasia

(Submitter supplied) Pla2g2f is dominantly expressed in the suprabasal layer of mouse epidermis. Microarray gene profiling supported the overall tendency of epidermal and sebaceous gland hyperplasia as well as alopecia in Pla2g2f-transgenic skin.

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL2872
2 Samples

Download data: TXT

Series

Accession:: GSE71829

ID:: 200071829

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000718273.

Transgenic overexpression of Pla2g10 display alopecia and epidermal hyperplasia

(Submitter supplied) Microarray gene profiling of skin from PLA2G10-Tg mice in comparison with that from control mice yielded data for explaining the overall tendency of Tg skin to show hair follicle distortion and epidermal hyperplasia associated with hyperkeratosis in the absence of inflammation

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL2872
2 Samples

Download data: TXT

Series

Accession:: GSE71827

ID:: 200071827

PubMed Full text in PMC Similar studies

Select item 2000718264.

Abnormal differentiation and activation of Pla2g2f-/- keratinocytes in primary culture

(Submitter supplied) Primary keratinocytes from Pla2g2f-/- mice were defective in proper differentiation and activation.

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL10333
4 Samples

Download data: TXT

Series

Accession:: GSE71826

ID:: 200071826

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2001964315.

Group IVE Cytosolic Phospholipase A2 Limits Psoriatic Inflammation by Mobilizing the Anti-inflammatory Lipid N-Acylethanolamine

(Submitter supplied) Psoriasis is an inflammatory disorder characterized by keratinocyte hyper-proliferation and Th17-type immune responses. However, the roles of bioactive lipids and the regulation of their biosynthesis in this chronic skin disease are not fully understood. Herein, we show that group IVE cytosolic phospholipase A2 (cPLA2epsilon/PLA2G4E) plays a counterregulatory role against psoriatic inflammation by producing the non-canonical anti-inflammatory lipid N-acylethanolamine (NAE). more...