GEO DataSets

Analysis of white blood cells (WBCs) from 5 males following exhaustive or moderate exercise. Results provide insight into the effects of exercise at the molecular level and the feasibility of using gene expression profiles of WBCs to monitor exercise and training load.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 5 individual, 4 time sets

Platform:

GPL571

Series:

GSE3606

20 Samples

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(Submitter supplied) White blood cells (WBCs) express tens of thousands of genes. Their expression levels are modified by genetic and external factors. The purpose of the present study was to investigate the effects of acute exercise on gene expression profiles (GEPs) of WBCs and to identify suitable genes which may serve as surrogate markers for monitoring exercise and training load. Five male probands performed an exhaustive treadmill test (ET) at 80% of their VO2max, and a moderate treadmill test (MT) at 60% VO2max for exactly the same time one to two week later. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS2310

Platform:

GPL571

20 Samples

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(Submitter supplied) Relatively brief bouts of exercise alter gene expression in peripheral blood mononuclear cells (PBMCs), but whether or not exercise changes gene expression in circulating neutrophils (whose numbers, like PBMCs, increase) is not known. We hypothesized that exercise would activate neutrophil genes involved in apoptosis, inflammation, and cell growth and repair, since these functions in leukocytes are known to be influenced by exercise. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS3073

Platform:

GPL570

24 Samples

Download data: CEL

Analysis of neutrophils from healthy males before and after 30 minutes of aerobic exercise. The number of circulating neutrophils increases after exercise. Results provide insight into the molecular response of these immune cells to exercise.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 12 individual, 2 protocol sets

Platform:

GPL570

Series:

GSE8668

24 Samples

Download data: CEL

(Submitter supplied) Analysis of peripheral blood mononuclear cells (PBMCs) separated from whole blood of healthy male subjects - prior to onset of exercise - immediately following the end of exercise and - immediately following 1 hour of recovery from exercise Keywords: other

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS962

Platform:

GPL96

15 Samples

Download data: CEL

Peripheral blood mononuclear cells (PBMC) were isolated from blood samples taken from healthy male subjects before, immediately after, and 60 minutes after 30 minutes of exercise. Brisk activation and deactivation of genes associated with stress, inflammation, and tissue repair observed.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 3 time sets

Platform:

GPL96

Series:

GSE1140

15 Samples

Download data: CEL

(Submitter supplied) cDNA microarray screening for gene expression changes in peripheral blood of eight half-marathon runners before (time point 0), immediately (time point 1) after and 24 h (time point 2) after exercise for details see publication: ... Keywords: repeat sample

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL1962

8 Samples

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(Submitter supplied) Time dependent-profiles in the gene expression level following lateral moderate fluid percussion injury in the rat brain We used microarray to elucidate relationship between the alteration of gene expression levels and the progression of brain damages following traumatic brain injury.

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Dataset:

GDS4911

Platform:

GPL1355

16 Samples

Download data: CEL

Analysis of lateral cortices of brains from Wistar males for up to 48 hours following traumatic brain injury (TBI). TBI induced by lateral moderate fluid percussion. Results provide insight into the nature of temporal events that occur at the molecular level following TBI.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, transformed count, 2 shock, 4 time sets

Platform:

GPL1355

Series:

GSE24047

16 Samples

Download data: CEL

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Homo sapiens

Type:

Expression profiling by array

Platforms:

GPL9454 GPL570

65 Samples

Download data: CEL

(Submitter supplied) The leg of healthy volunteers was locally deconditioned using three weeks of unilateral lower limb suspension (ULLS). The extremely deconditioned legs of subjects with a spinal cord injury (SCI) were trained using eight weeks of functional electrical stimulation (FES) exercise, 2-3 times per week (total 20 sessions). These models for local (in)activity were used to study changes in gene expression level of: A) Long-term deconditioning: before FES versus before ULLS (=SCI versus control); B) Short-term deconditioning: after ULLS versus before ULLS; and C) Exercise training: after FES versus before FES.

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL6244

14 Samples

Download data: CEL

(Submitter supplied) Subspecies of the Atlantic killifish, Fundulus heteroclitus, differ in their maximum thermal tolerance. To determine whether there is a link between the heat shock response (HSR) and maximum thermal tolerance, we exposed 20ºC acclimated killifish from these subspecies to a 2hr heat shock at 34ºC and examined gene expression during heat shock and recovery using real time quantitative PCR and a heterologous cDNA microarray designed for salmonid fishes. more...

Organism:

Osmerus mordax; Oncorhynchus mykiss; Oncorhynchus tshawytscha; Salmo salar; Fundulus heteroclitus; Coregonus clupeaformis

Type:

Expression profiling by array

Platform:

GPL2716

16 Samples

Download data: MEV

(Submitter supplied) Effects of voluntary exercise in rat aorta. Spontaneously hypertensive rats (SHR) performed 5 weeks of voluntary exercise (wheel-cage running). Aortic tissue was collected and samples were pooled (3 aortae/chip). Aortae from running rats were compared to aortae from non-running rats. Keywords: parallel sample

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Dataset:

GDS1301

Platform:

GPL85

6 Samples

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Expression profiling of the aorta of spontaneously hypertensive (SHR) females after 5 weeks of wheel-cage running. Results provide insight into the molecular mechanisms underlying improved cardiovascular health associated with exercise.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, count, 2 protocol sets

Platform:

GPL85

Series:

GSE2418

6 Samples

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(Submitter supplied) The immunological reaction to exercise has been investigated with increasing intensity in the last 10-20 years, with most human studies performed in male subjects. Recently, gender-specific aspects have received growing attention, but studies carefully monitoring the influence of gender, including the menstrual cycle, are rare. Here, we report gene expression patterns in response to a run at 93% of the individual anaerobic threshold of 9 women with regular menstrual cycles and no use of oral contraceptives who ran both at day 10 (follicular phase, F) and at day 25 (luteal phase, L) of their cycle. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL5676

6 Samples

Download data: TXT

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Homo sapiens

Type:

Expression profiling by array

Platforms:

GPL6487 GPL6488

60 Samples

Download data: CSV

(Submitter supplied) In comparison with allogeneic hematopoietic stem cell transplantation using other sources, umbilical cord blood transplantation (UCBT) offers substantial clinical advantages including a lower incidence and severity of acute graft-versus-host disease (GVHD) despite the use of allogeneic UCB stem cells with more disparate HLA. However, detailed pathophysiology of acute GVHD developed after UCBT has not yet been clarified. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL6488

40 Samples

Download data: CSV

(Submitter supplied) In comparison with allogeneic hematopoietic stem cell transplantation using other sources, umbilical cord blood transplantation (UCBT) offers substantial clinical advantages including a lower incidence and severity of acute graft-versus-host disease (GVHD) despite the use of allogeneic UCB stem cells with more disparate HLA. However, detailed pathophysiology of acute GVHD developed after UCBT has not yet been clarified. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL6487

20 Samples

Download data: CSV

(Submitter supplied) Cardiac hypertrophy was induced by treadmill running. Sedentary animals served as controls. Gene expression was determined by Affymetrix RGU34A GeneChip's to identify genes with differential expression in an adaptive model of cardiac hypertrophy. Keywords: other

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Dataset:

GDS654

Platform:

GPL85

12 Samples

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Analysis of heart left ventricles from animals subjected to 7 weeks treadmill exercise compared with sedentary controls. Provides insight into molecular mechanisms of left ventricular hypertrophy.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, count, 2 protocol sets

Platform:

GPL85

Series:

GSE739

12 Samples

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