Similar studies for GEO DataSets (Select 4209) - GEO DataSets

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Items: 5

Select item 42091.

Anti-CD47 antibody dimer MABL (S-S diabody) effect on leukemia cell line: time course

Temporal analysis of MOLT-4 leukemia cells treated with 10 ug/mL anti-CD47 dimer MABL (S-S diabody). Cell surface antigen CD47 ligation induces apoptosis in B-chronic lymphocytic leukemia. Results provide insight into the molecular mechanism of CD47-mediated apoptosis in lymphoid malignant cells.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 5 time sets

Platform:: GPL96
Series:: GSE16494
10 Samples

Download data: CEL

DataSet

Accession:: GDS4209

ID:: 4209

Select item 2000164942.

Expression profiling MOLT-4 treated with MABL

(Submitter supplied) Analysis of MOLT-4 cells at various time points up to 6 hours following treatment with mouse anti-CD47 antibody (MABL) and goat anti-mouse IgG (GAM) as the crosslinker of MABL. MABL induces apoptosis in CD47-positive MOLT-4 cells. Cell death signals via CD47 ligation were analyzed by using Affymetrix Human Genome U133A microarray.

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS4209
Platform:: GPL96
10 Samples

Download data: CEL

Series

Accession:: GSE16494

ID:: 200016494

Select item 2000771733.

Gene expression profiling of Mec-1 cells upon chronic silencing of HIF-1a

(Submitter supplied) This experiment was carried out in the context of a study aimed to identify the function of the transcription facotrs HIF-1a in the pathogenesis of chronic lymphocytic leukemia (CLL).

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL6884
2 Samples

Download data: TXT

Series

Accession:: GSE77173

ID:: 200077173

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2001791964.

Gene expression in murine chronic lymphocytic leukemia B cells

(Submitter supplied) mRNA profiles were generated by 3'-sequencing, in triplicate from B cells of control mice (AHRWT/WT Hif1aWT/WT), AHR conditional KO (AHRfl/fl), Hif1a conditional KO (Hif1afl/fl) or double AHR and Hif1a conditional KO (AHRfl/fl Hif1afl/fl) .

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing

Platform:: GPL24247
12 Samples

Download data: TXT

Series

Accession:: GSE179196

ID:: 200179196

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2001755645.

Gene expression in murine chronic lymphocytic leukemia

(Submitter supplied) mRNA profiles of B cells from 8-week-old wild-type (WT) and leukemic (Eu-TCL1) mice were generated by 3'-sequencing, in triplicate.