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Links from GEO DataSets

Items: 4

1.
Full record GDS4517

Model for the manic pole of bipolar disorder: hippocampus

Analysis of hippocampi from Madison (MSN) and hsd:ICR (ICR) adult males. The inbred MSN strain displays a naturally manic phenotype relative to the outbred ICR ancestral strain. Results provide insight into molecular mechanisms underlying the manic pole of bipolar disorder.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 strain sets
Platform:
GPL6246
Series:
GSE29417
12 Samples
Download data: CEL
2.

A new mouse model for mania shares genetic correlates with human bipolar disorder.

(Submitter supplied) Bipolar disorder (BPD) is a debilitating heritable psychiatric disorder. Contemporary models for the manic pole of BPD have primarily utilized either single locus transgenics or treatment with psychostimulants. Our lab recently characterized a mouse strain, termed Madison (MSN), which naturally displays a manic phenotype, exhibiting elevated locomotor activity, increased sexual behavior, and higher forced swimming relative to control strains. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Dataset:
GDS4517
Platform:
GPL6246
12 Samples
Download data: CEL
Series
Accession:
GSE29417
ID:
200029417
3.

Gene Expression in Blood in Scizophrenia and Bipolar Disorder

(Submitter supplied) Schizophrenia (SCZ) and bipolar disorder (BPD) are polygenic disorders with many genes contributing to their etiologies. The aim of this investigation was to search for dysregulated molecular and cellular pathways for these disorders as well as psychosis. We conducted a blood-based microarray investigation in two independent samples with SCZ and BPD from San Diego (SCZ=13, BPD=9, control=8) and Taiwan [data not included](SCZ=11, BPD=14, control=16). more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL5175
30 Samples
Download data: CEL
Series
Accession:
GSE18312
ID:
200018312
4.

Peripheral blood gene-expression in depressed subjects with bipolar disorder vs healthy controls.

(Submitter supplied) Analysis of gene-expression changes in depressed subjects with bipolar disorder compared to healthy controls. Results provide information on pathways that may be involved in the pathogenesis of bipolar depression.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL6106
35 Samples
Download data: TXT
Series
Accession:
GSE23848
ID:
200023848
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Supplemental Content

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