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Links from GEO DataSets

Items: 20

1.
Full record GDS525

Extraocular and limb muscle comparison

Molecular definition of extraocular muscle (EOM). Autopsy superior rectus EOM compared with biopsy limb quadriceps femoris muscle.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 tissue sets
Platform:
GPL96
Series:
GSE873
5 Samples
Download data: CEL
DataSet
Accession:
GDS525
ID:
525
2.

Muscle, normal extraocular, profile

(Submitter supplied) Molecular definition of human extraocular muscles (EOM). Human EOM were compared with limb (quadriceps femoris) muscle. Keywords = Eye Keywords = EOM Keywords = Muscle Keywords = DMD Keywords = Myasthenia Gravis Keywords: other
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS525
Platform:
GPL96
5 Samples
Download data: CEL
Series
Accession:
GSE873
ID:
200000873
3.

Expression profiling of extraocular muscles

(Submitter supplied) The extraocular muscles (EOM) are anatomically and physiologically distinct from other skeletal muscles. EOM are preferentially affected in mitochondrial myopathies, but spared in Duchenne's muscular dystrophy. The anatomical and pathophysiological properties of EOM have been attributed to their unique molecular makeup: an allotype. We used expression profiling to define molecular features of the EOM allotype. more...
Organism:
Rattus norvegicus
Type:
Expression profiling by array
Dataset:
GDS254
Platform:
GPL85
16 Samples
Download data: CEL
Series
Accession:
GSE471
ID:
200000471
4.
Full record GDS254

Muscle, normal extraocular, profile

Molecular definition of extraocular muscles (EOM). EOM are anatomically and physiologically distinct from other skeletal muscles.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 2 tissue sets
Platform:
GPL85
Series:
GSE471
16 Samples
Download data: CEL
DataSet
Accession:
GDS254
ID:
254
5.

Laminar gene expression of rat extraocular orbital and global layers

(Submitter supplied) Adult rat global and orbital layers of rectal extraocular muscles microdissected using Arcturus Pixcell II LCM are gene profiled here using affymetrix rat RAE230A gene chip. www.med.upenn.edu/cellbio/faculty/rubinstein/ www.uphs.upenn.edu/pmi/members/khurana/lab%20page.htm Keywords: ordered
Organism:
Rattus norvegicus
Type:
Expression profiling by array
Dataset:
GDS851
Platform:
GPL341
8 Samples
Download data
Series
Accession:
GSE1374
ID:
200001374
6.
Full record GDS851

Extraocular muscle: comparison of global and orbital layers

Expression profiling of microdissected global and orbital layers of the rectus extraocular muscle (EOM) from 2 adult Sprague-Dawleys. By identifying molecular differences between the 2 layers, results provide insight into the possible specialized function of each muscle layer.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 2 tissue sets
Platform:
GPL341
Series:
GSE1374
8 Samples
Download data
DataSet
Accession:
GDS851
ID:
851
7.

EOM and hindlimb muscle development

(Submitter supplied) Conserved and muscle group-specific gene expression patterns shape postnatal development of the novel extraocular muscle phenotype. Comparison of postnatal development of extraocular and hindlimb muscle between birth and P45. Keywords: parallel sample
Organism:
Rattus norvegicus
Type:
Expression profiling by array
Dataset:
GDS621
Platform:
GPL85
36 Samples
Download data: CEL
Series
Accession:
GSE903
ID:
200000903
8.
Full record GDS621

Extraocular and hindlimb muscle development

Analysis of hindlimb and extraocular muscle (EOM) between birth and postnatal day 45. Dissecting allotype-specific regulatory mechanisms may help explain differential muscle group sensitivity to a variety of metabolic and neuromuscular diseases.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 6 age, 2 tissue sets
Platform:
GPL85
Series:
GSE903
36 Samples
Download data: CEL
DataSet
Accession:
GDS621
ID:
621
9.

Effect of Oxandrolone on Muscle in Duchenne Muscular Dystrophy

(Submitter supplied) Three subjects with Duchenne muscular dystrophy (8.3, 10.4, and 16.7 years old) were studied. Baseline studies included stable isotope infusion followed by gastrocnemius muscle biopsy to determine myosin heavy chain synthesis rates. RNA was isolated from the muscle biopsy as well. The subjects were then treated for 3 months with oxandrolone (a synthetic anabolic steroid, 0.1 mg/kg/day) and the studies repeated. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Datasets:
GDS1333 GDS1334
Platforms:
GPL96 GPL97
12 Samples
Download data
Series
Accession:
GSE1764
ID:
200001764
10.
Full record GDS1334

Duchenne Muscular Dystrophy response to oxandrolone (HG-U133B)

Analysis of gastrocnemius muscle biopsy specimens from Duchenne muscular dystrophy (DMD) patients before and after 3 months of treatment with 0.1mg/kg/day oxandrolone, a synthetic anabolic steroid. Results provide insight into mechanisms underlying the beneficial effect of oxandrolone in DMD.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 agent, 3 individual sets
Platform:
GPL97
Series:
GSE1764
6 Samples
Download data
DataSet
Accession:
GDS1334
ID:
1334
11.
Full record GDS1333

Duchenne Muscular Dystrophy response to oxandrolone (HG-U133A)

Analysis of gastrocnemius muscle biopsy specimens from Duchenne muscular dystrophy (DMD) patients before and after 3 months of treatment with 0.1mg/kg/day oxandrolone, a synthetic anabolic steroid. Results provide insight into mechanisms underlying the beneficial effect of oxandrolone in DMD.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 agent, 3 individual sets
Platform:
GPL96
Series:
GSE1764
6 Samples
Download data
DataSet
Accession:
GDS1333
ID:
1333
12.

EOM and TA Sp cell comparison

(Submitter supplied) Using Affymetrix GeneChips, we analyzed expression profiles of SP cells from EOM and TA. 348 differentially expressed transcripts defined the EOM-SP transcriptome: 229 upregulated in EOM-SP and 119 in TA-SP. Keywords: Expression Profiling
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL1261
12 Samples
Download data: CEL
Series
Accession:
GSE9294
ID:
200009294
13.

microRNA profiling of extraocular muscles

(Submitter supplied) The extraocular muscles (EOMs) are a unique group of muscles that are anatomically and physiologically distinct from other skeletal muscles. Previously, we and others have shown that EOMs have a unique transcriptome and proteome. Here, we investigated the expression pattern of microRNAs (miRNAs) in EOM, as they may play a role in generating the unique EOM allotype. We screened LC Sciences miRNA microarrays covering the sequences of miRBase 10.0 to define the microRNAome of normal mouse EOM and tibialis anterior (TA) limb muscle. more...
Organism:
Mus musculus
Type:
Non-coding RNA profiling by array
Platform:
GPL8605
8 Samples
Download data: TXT
Series
Accession:
GSE18538
ID:
200018538
14.

Time course Healthy DMD myogenesis

(Submitter supplied) Primairy human myoblast cell cultures Healthy DMD Keywords: time-course
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL2097
42 Samples
Download data
Series
Accession:
GSE2693
ID:
200002693
15.

A transcriptional map of the impact of endurance exercise training on skeletal muscle phenotype

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platforms:
GPL9454 GPL570
65 Samples
Download data: CEL
Series
Accession:
GSE35661
ID:
200035661
16.

Extraocular muscle, expression changes in critical period (Porter lab)

(Submitter supplied) Evaluation of extraocular muscle (EOM) critical period by expression profiling in dark reared rat. Data form part of publication: Investigative Ophthalmology and Visual Sciences 44: 3842-3855, 2003. Keywords: other
Organism:
Rattus norvegicus
Type:
Expression profiling by SAGE
Platform:
GPL23
2 Samples
Download data
Series
Accession:
GSE497
ID:
200000497
17.

Normal human muscle - U133 arrays

(Submitter supplied) vastus lateralis biopsies were obtained from healthy subjects, either young adults (20-29 yr old) or older (65-75 yr old) Keywords = muscle Keywords = aging Keywords: other
Organism:
Homo sapiens
Type:
Expression profiling by array
Datasets:
GDS287 GDS288
Platforms:
GPL96 GPL97
30 Samples
Download data
Series
Accession:
GSE362
ID:
200000362
18.
Full record GDS288

Muscle function and aging - male (HG-U133B)

Comparison of gene expression in vastus lateralis skeletal muscle biopsies in healthy young (21-27 year old) and older (67-75 year old) men.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 age sets
Platform:
GPL97
Series:
GSE362
15 Samples
Download data
DataSet
Accession:
GDS288
ID:
288
19.
Full record GDS287

Muscle function and aging - male (HG-U133A)

Comparison of gene expression in vastus lateralis skeletal muscle biopsies in healthy young (21-27 year old) and older (67-75 year old) men
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 age sets
Platform:
GPL96
Series:
GSE362
15 Samples
Download data
DataSet
Accession:
GDS287
ID:
287
20.

Expression data of normal human extraocular muscle and strabismic human extraocular muscle

(Submitter supplied) Human strabismic extraocular muscles (EOMs) differ from normal EOMs in structural and functional properties, but the gene expression profile of these two types of human EOM has not been examined. Differences in gene expression may inform about causes and effects of the strabismic condition in humans. Our samples are from human strabismic patients undergoing corrective surgery, and from human organ donors with no history of EOM disease. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL570
8 Samples
Download data: CEL
Series
Accession:
GSE38780
ID:
200038780
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