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Links from GEO DataSets

Items: 20

1.
Full record GDS563

Duchenne muscular dystrophy (II) (HG-U95A)

Search for modifying factors and pathogenic pathways involved in Duchenne muscular dystrophy (DMD). Quadricep skeletal muscle biopsies from 12 DMD patients and 11 unaffected control patients examined.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 disease state sets
Platform:
GPL8300
Series:
GSE1004
23 Samples
Download data: CEL, EXP, RPT
2.

Molecular profiles (HG-U95A) of dystrophin-deficient and normal human muscle

(Submitter supplied) Molecular profiles of dystophin-deficient patients and normal human skeletal muscles on Affymetrix HG-U95A arrays Keywords = DMD Keywords = Duchenne muscular dystrophy Keywords = dystrophin Keywords = Affymetrix U95A array Keywords = skeletal muscle Keywords = gene expression profiles Keywords: other
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS563
Platforms:
GPL8300 GPL91
24 Samples
Download data: CEL, EXP, RPT
Series
Accession:
GSE1004
ID:
200001004
3.

Molecular profiles(HG-U95B,C,D,E) of dystrophin-deficient and normal human skeletal muscle

(Submitter supplied) molecular profiles (HG-U95B,C,D,E) of biopsy skeletal muscle samples obtained from 10 normal individuals and 10 DMD patients Keywords = gene expression profiles of normal human skeletal muscles Keywords = gene expression profiles of DMD patients' skelatal muscle samples Keywords = Affymetrix HG-U95B Keywords = Affymetrix HG-U95C Keywords = Affymetrix HG-U95D Keywords = Affymetrix HG-U95E Keywords: other
Organism:
Homo sapiens
Type:
Expression profiling by array
Datasets:
GDS609 GDS610 GDS611 GDS612
4 related Platforms
86 Samples
Download data: CEL, EXP, RPT
Series
Accession:
GSE1007
ID:
200001007
4.
Full record GDS612

Duchenne muscular dystrophy (II) (HG-U95E)

Search for modifying factors and pathogenic pathways involved in Duchenne muscular dystrophy (DMD). Quadricep skeletal muscle biopsies from DMD patients and unaffected control patients examined.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 disease state sets
Platform:
GPL95
Series:
GSE1007
21 Samples
Download data: CEL, EXP, RPT
DataSet
Accession:
GDS612
ID:
612
5.
Full record GDS611

Duchenne muscular dystrophy (II) (HG-U95D)

Search for modifying factors and pathogenic pathways involved in Duchenne muscular dystrophy (DMD). Quadricep skeletal muscle biopsies from DMD patients and unaffected control patients examined.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 disease state sets
Platform:
GPL94
Series:
GSE1007
22 Samples
Download data: CEL, EXP, RPT
DataSet
Accession:
GDS611
ID:
611
6.
Full record GDS610

Duchenne muscular dystrophy (II) (HG-U95C)

Search for modifying factors and pathogenic pathways involved in Duchenne muscular dystrophy (DMD). Quadricep skeletal muscle biopsies from DMD patients and unaffected control patients examined.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 disease state sets
Platform:
GPL93
Series:
GSE1007
22 Samples
Download data: CEL, EXP, RPT
DataSet
Accession:
GDS610
ID:
610
7.
Full record GDS609

Duchenne muscular dystrophy (II) (HG-U95B)

Search for modifying factors and pathogenic pathways involved in Duchenne muscular dystrophy (DMD). Quadricep skeletal muscle biopsies from DMD patients and unaffected control patients examined.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 disease state sets
Platform:
GPL92
Series:
GSE1007
21 Samples
Download data: CEL, EXP, RPT
DataSet
Accession:
GDS609
ID:
609
8.

Diaphram, comparison of wild type and mdx mice, 7 to 112 Days (Porter lab)

(Submitter supplied) Determination of gene expression changes in extraocular muscle of mdx (dystrophin-deficient) mice at postnatal ages 7, 14, 23, 28, 56, and 112 days. 3 independent replicates/age/strain. Data form part of publication: Human Molecular Genetics 13:257-269, 2004. Keywords = microarray Keywords = muscle Keywords: time-course
Organism:
Mus musculus
Type:
Expression profiling by array
Dataset:
GDS638
Platform:
GPL81
36 Samples
Download data: CEL
Series
Accession:
GSE1026
ID:
200001026
9.
Full record GDS638

Dystrophin-deficient mdx diaphram muscle development time course

Temporal analysis of diaphram muscle from dystrophin-deficient mdx mice, a Duchenne muscular dystrophy (DMD) model. Postnatal ages 7 to 112 days examined. Results provide insight into mechanisms of muscular dystrophy pathogenesis.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 6 age, 2 strain sets
Platform:
GPL81
Series:
GSE1026
36 Samples
Download data: CEL
DataSet
Accession:
GDS638
ID:
638
10.

A transcriptional map of the impact of endurance exercise training on skeletal muscle phenotype

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platforms:
GPL9454 GPL570
65 Samples
Download data: CEL
Series
Accession:
GSE35661
ID:
200035661
11.

Time-course of mdx and wild type mice

(Submitter supplied) Time-course microarray data set of mdx and wild type mice ranging from 1-20 weeks of age Keywords: time-course
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL485
36 Samples
Download data
Series
Accession:
GSE1574
ID:
200001574
12.

Extraocular and hindlimb muscle, comparison of wild type and mdx mice, 56 days (Porter lab)

(Submitter supplied) Determination of gene expression changes in extraocular and hindlimb (gastrocnemius/soleus) of mdx (dystrophin-deficient) mice at postnatal day 56. 5 independent replicates/muscle group/strain. Keywords: parallel sample
Organism:
Mus musculus
Type:
Expression profiling by array
Dataset:
GDS703
Platform:
GPL32
20 Samples
Download data: CEL
Series
Accession:
GSE1472
ID:
200001472
13.
Full record GDS703

Dystrophin-deficient mdx extraocular and leg muscle

Analysis of extraocular (EOM) and hindlimb (gastrocnemius/soleus) muscle in mdx (dystrophin-deficient; Duchenne muscular dystrophy model) mice at postnatal day 56.5. Highly specific changes observed between dystrophic (leg) and spared (EOM) muscle.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 strain, 2 tissue sets
Platform:
GPL32
Series:
GSE1472
20 Samples
Download data: CEL
DataSet
Accession:
GDS703
ID:
703
14.

Time course Healthy DMD myogenesis

(Submitter supplied) Primairy human myoblast cell cultures Healthy DMD Keywords: time-course
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL2097
42 Samples
Download data
Series
Accession:
GSE2693
ID:
200002693
15.

Effect of Oxandrolone on Muscle in Duchenne Muscular Dystrophy

(Submitter supplied) Three subjects with Duchenne muscular dystrophy (8.3, 10.4, and 16.7 years old) were studied. Baseline studies included stable isotope infusion followed by gastrocnemius muscle biopsy to determine myosin heavy chain synthesis rates. RNA was isolated from the muscle biopsy as well. The subjects were then treated for 3 months with oxandrolone (a synthetic anabolic steroid, 0.1 mg/kg/day) and the studies repeated. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Datasets:
GDS1333 GDS1334
Platforms:
GPL96 GPL97
12 Samples
Download data
Series
Accession:
GSE1764
ID:
200001764
16.
Full record GDS1334

Duchenne Muscular Dystrophy response to oxandrolone (HG-U133B)

Analysis of gastrocnemius muscle biopsy specimens from Duchenne muscular dystrophy (DMD) patients before and after 3 months of treatment with 0.1mg/kg/day oxandrolone, a synthetic anabolic steroid. Results provide insight into mechanisms underlying the beneficial effect of oxandrolone in DMD.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 agent, 3 individual sets
Platform:
GPL97
Series:
GSE1764
6 Samples
Download data
DataSet
Accession:
GDS1334
ID:
1334
17.
Full record GDS1333

Duchenne Muscular Dystrophy response to oxandrolone (HG-U133A)

Analysis of gastrocnemius muscle biopsy specimens from Duchenne muscular dystrophy (DMD) patients before and after 3 months of treatment with 0.1mg/kg/day oxandrolone, a synthetic anabolic steroid. Results provide insight into mechanisms underlying the beneficial effect of oxandrolone in DMD.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 agent, 3 individual sets
Platform:
GPL96
Series:
GSE1764
6 Samples
Download data
DataSet
Accession:
GDS1333
ID:
1333
18.

Degenerative and Regenerative Pathways Underlying Duchenne Muscular Dystrophy Revealed by Single-nucleus RNA sequencing

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL19057
8 Samples
Download data: MTX, TSV
Series
Accession:
GSE156498
ID:
200156498
19.

Single nucleus RNA-seq analysis of the TA muscles from WT and Dmd Exon 51 Knockout mice

(Submitter supplied) Duchenne muscular dystrophy (DMD) is a fatal muscle disorder characterized by cycles of degeneration and regeneration of multinucleated myofibers and pathological activation of a variety of other associated cell types. Here, we describe the creation of a new mouse model of DMD caused by deletion of exon 51 of the dystrophin gene, which represents a prevalent mutation in humans. To understand the transcriptional abnormalities and heterogeneity associated with the nuclei of myofibers, as well as other mononucleated cell types that contribute to DMD disease pathogenesis, we performed single nucleus transcriptomics of skeletal muscle of mice with exon 51 deletion. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL19057
2 Samples
Download data: MTX, TSV
Series
Accession:
GSE156497
ID:
200156497
20.

Transcriptome analysis of the TA muscles from WT and Dmd Exon 51 Knockout mice

(Submitter supplied) Duchenne muscular dystrophy (DMD) is a fatal muscle disorder characterized by cycles of degeneration and regeneration of multinucleated myofibers and pathological activation of a variety of other associated cell types. Here, we describe the creation of a new mouse model of DMD caused by deletion of exon 51 of the dystrophin gene, which represents a prevalent mutation in humans. To understand the transcriptional abnormalities and heterogeneity associated with the nuclei of myofibers, as well as other mononucleated cell types that contribute to DMD disease pathogenesis, we performed single nucleus transcriptomics of skeletal muscle of mice with exon 51 deletion. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL19057
6 Samples
Download data: TXT
Series
Accession:
GSE156496
ID:
200156496
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