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Links from GEO DataSets

Items: 9

1.
Full record GDS677

4-nonylphenol effect on liver

Analysis of FVB/NJ liver treated with 45 mg/kg/day 4-nonylphenol (4-NP) for 32 weeks. 4-NP is an industrial waste and elicits estrogen-like responses. Results provide insight into molecular events altered by 4-NP.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 agent sets
Platform:
GPL144
Series:
GSE1083
4 Samples
Download data
DataSet
Accession:
GDS677
ID:
677
2.

Alterations in gene expression in FVB/NJ mouse liver following 4-nonylphenol (4-NP) treatment for 32 weeks

(Submitter supplied) Alterations in gene expression in FVB/NJ mouse liver following 4-nonylphenol (4-NP) treatment for 32 weeks. Mice were treated with 45 mg/kg/day 4-NP for 32 weeks, livers excised and differential gene expression determined. Samples 1 and 2 are controls and samples 3 and 4 are mice treated with 4-NP. Arrays were visualized from the K-screen, and analyzed and quantified with a phosphoimager (Molecular Imager FX, Bio-Rad, Hercules, CA) and the ResGen PathwaysTM Universal Microarray Analysis SoftwareTM (Research Genetics, Carlsbad, CA). more...
Organism:
Mus musculus
Type:
Expression profiling by array
Dataset:
GDS677
Platform:
GPL144
4 Samples
Download data
Series
Accession:
GSE1083
ID:
200001083
3.

SYSTEMS ANALYSIS OF THE LIVER TRANSCRIPTOME IN ADULT MALE ZEBRAFISH EXPOSED TO THE NON-IONIC SURFACTANT NONYLPHENOL (NP).

(Submitter supplied) We report the effects of exposure to the endocrine disruptor nonylphenol (NP) on transcriptome modification in the livers of in vivo Zebrafish. Our data indicate changes in fatty acid metabolism and inflammation, pathways associated with the development of Non-Alcoholic Fatty Liver Disease (NAFLD).
Organism:
Danio rerio
Type:
Expression profiling by high throughput sequencing
Platform:
GPL15583
6 Samples
Download data: TXT
Series
Accession:
GSE100369
ID:
200100369
4.

The steroid hormone estriol (E3) regulates epigenetic programming of fetal mouse brain and reproductive tract [methylation]

(Submitter supplied) We identify an unexpected functional role for E3 in fetal reproductive system and brain. We further identify a novel mechanism of estrogen action, through recruitment of epigenetic modifiers to estrogen receptors and their target genes, which doesn’t correlated with the traditional view of estrogen potency.”
Organism:
Mus musculus
Type:
Methylation profiling by high throughput sequencing
Platform:
GPL21103
4 Samples
Download data: CSV, TXT, XLS, XLSX
Series
Accession:
GSE199434
ID:
200199434
5.

The steroid hormone estriol (E3) regulates epigenetic programming of fetal mouse brain and reproductive tract [ChIP-Seq]

(Submitter supplied) We identify an unexpected functional role for E3 in fetal reproductive system and brain. We further identify a novel mechanism of estrogen action, through recruitment of epigenetic modifiers to estrogen receptors and their target genes, which doesn’t correlated with the traditional view of estrogen potency.”
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL16791
8 Samples
Download data: BEDGRAPH
Series
Accession:
GSE199293
ID:
200199293
6.

The steroid hormone estriol (E3) regulates epigenetic programming of fetal mouse brain and reproductive tract

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens; Mus musculus
Type:
Expression profiling by array; Methylation profiling by genome tiling array; Genome binding/occupancy profiling by high throughput sequencing; Methylation profiling by high throughput sequencing
4 related Platforms
24 Samples
Download data: BEDGRAPH, CEL, CHP, GFF
Series
Accession:
GSE199214
ID:
200199214
7.

The steroid hormone estriol (E3) regulates epigenetic programming of fetal mouse brain and reproductive tract [NimbleGen]

(Submitter supplied) We identify an unexpected functional role for E3 in fetal reproductive system and brain. We further identify a novel mechanism of estrogen action, through recruitment of epigenetic modifiers to estrogen receptors and their target genes, which doesn’t correlated with the traditional view of estrogen potency.
Organism:
Mus musculus
Type:
Methylation profiling by genome tiling array
Platform:
GPL18163
4 Samples
Download data: GFF, XLSX
Series
Accession:
GSE199213
ID:
200199213
8.

The steroid hormone estriol (E3) regulates epigenetic programming of fetal mouse brain and reproductive tract [Affymetrix]

(Submitter supplied) We identify an unexpected functional role for E3 in fetal reproductive system and brain. We further identify a novel mechanism of estrogen action, through recruitment of epigenetic modifiers to estrogen receptors and their target genes, which doesn’t correlated with the traditional view of estrogen potency.
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL20775
8 Samples
Download data: CEL, CHP
Series
Accession:
GSE199174
ID:
200199174
9.

Transcriptomic Analysis of Nonylphenol Effect on Saccharomyces cerevisiae

(Submitter supplied) Nonylphenol (NP), is a bioaccumulative environmental estrogen that is widely used as a nonionic surfactant. We have previously examined short-term effects of NP on yeast cells using microarray technology. In the present study, we investigated the long-term impacts of NP on Saccharomyces cerevisiae BY4742 cells by analyzing genome-wide transcriptional profiles using RNA-sequencing. We used 2 mg/L NP concentration exposure for 40 days. more...
Organism:
Saccharomyces cerevisiae
Type:
Expression profiling by high throughput sequencing
Platform:
GPL25927
6 Samples
Download data: XLSX
Series
Accession:
GSE158124
ID:
200158124
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Supplemental Content

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