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Full record GDS2346

Reticulocyte binding-like homolog 2b knockout effect on 3D7 parasites

Analysis of reticulocyte binding-like homolog 2b (PfRh2b) null mutant 3D7 parasites. D10 isolate naturally lacks PfRh2b. Silencing of PfRh2b, a key invasion ligand, leads to altered invasion receptor dependency. Results provide insight into the molecular basis for invasion via an alternate pathway.
Organism:
Plasmodium falciparum
Type:
Expression profiling by array, transformed count, 2 development stage, 5 genotype/variation, 2 strain sets
Platform:
GPL1892
Series:
GSE3877
10 Samples
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