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Full record GDS4071

TGFβ1 effect on HMEC-TR mammary epithelial cell line deficient in Smad4 or TIF1γ

Analysis of HMEC-TR cells silenced for TIF1γ or Smad4 and treated with TGFβ. A strong EMT increase was observed in TIF1γ-silenced cells after TGFβ1 treatment; Smad4 inactivation completely blocked this process. Results show the relationship between TIF1γ and Smad4 in TGF-β signaling and EMT.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 agent, 3 genotype/variation sets
Platform:
GPL570
Series:
GSE28448
11 Samples
Download data: CEL, CHP

Supplemental Content

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  • Related DataSets for GEO Profiles (Select 77973407) (1)
    GEO DataSets
  • TGFβ1 effect on HMEC-TR mammary epithelial cell line deficient in Smad4 or TIF1γ...
    TGFβ1 effect on HMEC-TR mammary epithelial cell line deficient in Smad4 or TIF1γ
    Accession: GDS4071
    GEO DataSets
  • Chromosome neighbors for GEO Profiles (Select 77975828) (18)
    GEO Profiles
  • PopSet Links for Protein (Select 1904996154) (1)
    PopSet
  • Aves tRNA-Phe (trnF(gaa)), 12S ribosomal RNA, tRNA-Val (trnV(uac)), 16S ribosoma...
    Aves tRNA-Phe (trnF(gaa)), 12S ribosomal RNA, tRNA-Val (trnV(uac)), 16S ribosomal RNA, and tRNA-Leu (trnL(uaa)) genes, complete sequence; NADH dehydrogenase subunit 1 (ND1) gene, complete cds; tRNA-Ile (trnI(gau)), tRNA-Gln (trnQ(uug)), and tRNA-Met (trnM(cau)) genes, complete sequence; NADH dehydrogenase subunit 2 (ND2) gene, complete cds; tRNA-Trp (trnW(uca)), tRNA-Ala (trnA(ugc)), tRNA-Asn (trnN(guu)), tRNA-Cys (trnC(gca)), and tRNA-Tyr (trnY(gua)) genes, complete sequence; cytochrome c oxidase subunit I (COX1) gene, complete cds; tRNA-Ser (trnS(uga)) and tRNA-Asp (trnD(guc)) genes, complete sequence; cytochrome c oxidase subunit II (COX2) gene, complete cds; tRNA-Lys (trnK(uuu)) gene, complete sequence; ATP synthase F0 subunit 8 (ATP8), ATP synthase F0 subunit 6 (ATP6), and cytochrome c oxidase subunit III (COX3) genes, complete cds; tRNA-Gly (trnG(ucc)) gene, complete sequence; NADH dehydrogenase subunit 3 (ND3) gene, complete cds; tRNA-Arg (trnR(ucg)) gene, complete sequence; NADH dehydrogenase subunit 4L (ND4L) and NADH dehydrogenase subunit 4 (ND4) genes, complete cds; tRNA-His (trnH(gug)), tRNA-Ser (trnS(gcu)), and tRNA-Leu (trnL(uag)) genes, complete sequence; NADH dehydrogenase subunit 5 (ND5) and cytochrome b (CYTB) genes, complete cds; and tRNA-Thr (trnT(ugu)) gene, complete sequence; mitochondrial.
    PopSet: 1904995940
    PopSet

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