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Full record GDS4071

TGFβ1 effect on HMEC-TR mammary epithelial cell line deficient in Smad4 or TIF1γ

Analysis of HMEC-TR cells silenced for TIF1γ or Smad4 and treated with TGFβ. A strong EMT increase was observed in TIF1γ-silenced cells after TGFβ1 treatment; Smad4 inactivation completely blocked this process. Results show the relationship between TIF1γ and Smad4 in TGF-β signaling and EMT.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 agent, 3 genotype/variation sets
Platform:
GPL570
Series:
GSE28448
11 Samples
Download data: CEL, CHP

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