GEO DataSet Links for PMC (Select 3079247) - GEO DataSets

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Links from PMC

Items: 3

Select item 2000250961.

HoxA3 is an apical regulator of hemogenic endothelium

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Expression profiling by array

Platforms:: GPL6238 GPL4134
24 Samples

Download data: TXT

Series

Accession:: GSE25096

ID:: 200025096

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000250802.

Genes regulated by HoxA3 in endothelial and hematopoietic progenitors

(Submitter supplied) We used a murine ES cell line in which HoxA3 expression is under control of a tetracycline-responsive element and differentiated these cells as embryoid bodies (EBs). Endothelial (Flk-1 VE-cadherin double positive, FV) and hematopoieitc progenitors (c-Kit CD41 double positive, K41) were isolated from differentiated EBs that had been induced for 6 hours by doxycycline (Dox) treatment.

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL6238
12 Samples

Download data: TXT

Series

Accession:: GSE25080

ID:: 200025080

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000250793.

Epistasis analysis of Runx1 and Gata1 over HoxA3 in hemogenic endothelium

(Submitter supplied) We observe that HoxA3 represses hematopoieis by the repression of several transcription factors including Runx1 and Gata1. Up regulation of either Runx1 or Gata1 in the presence of HoxA3 reverted the hematopoietic repression. We have performed full genome analysis to determine the molecular signature of hematopoietic development in response to upregulation of Runx1 and Gata1.