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Items: 3

1.

A functional portrait of Med7 and the Mediator complex in Candida albicans

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Candida albicans
Type:
Expression profiling by array; Genome binding/occupancy profiling by genome tiling array
Platforms:
GPL19196 GPL10636
9 Samples
Download data: TXT
Series
Accession:
GSE61519
ID:
200061519
2.

A functional portrait of Med7 and the Mediator complex in Candida albicans [ChIP-chip]

(Submitter supplied) In this study, we have investigated Mediator function in the human fungal pathogen C. albicans. An initial screening of conditionally regulated Mediator subunits showed that the Med7 of C. albicans was not essential, in contrast to the situation noted for Saccharomyces cerevisiae. While loss of CaMed7 did not lead to loss of viability under normal growth conditions, it dramatically influenced the pathogen’s ability to grow in different carbon sources, to form hyphae and biofilms, and to colonize the gastrointestinal tracts of mice. more...
Organism:
Candida albicans
Type:
Genome binding/occupancy profiling by genome tiling array
Platform:
GPL10636
4 Samples
Download data: TXT
Series
Accession:
GSE61518
ID:
200061518
3.

A functional portrait of Med7 and the Mediator complex in Candida albicans [expression]

(Submitter supplied) In this study, we have investigated Mediator function in the human fungal pathogen C. albicans. An initial screening of conditionally regulated Mediator subunits showed that the Med7 of C. albicans was not essential, in contrast to the situation noted for Saccharomyces cerevisiae. While loss of CaMed7 did not lead to loss of viability under normal growth conditions, it dramatically influenced the pathogen’s ability to grow in different carbon sources, to form hyphae and biofilms, and to colonize the gastrointestinal tracts of mice. more...
Organism:
Candida albicans
Type:
Expression profiling by array
Platform:
GPL19196
5 Samples
Download data: TXT
Series
Accession:
GSE61469
ID:
200061469
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