GEO DataSet Links for PMC (Select 4809300) - GEO DataSets

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Items: 2

Select item 2000738411.

The purine metabolite allantoin can activate the jasmonate signaling pathway in a MYC2-regulated and ABA-dependent manner

(Submitter supplied) Allantoin is a metabolic intermediate of purine catabolism that often accumulates in stressed plants. Recently, using Arabidopsis knockout mutants (aln) of ALLANTOINASE, we showed that this purine metabolite activates ABA production, thereby stimulating stress-related gene expression and enhancing seedling tolerance to abiotic stress. A detailed re-examination of the microarray data of an aln mutant (aln-1) not only confirmed increased expression of ABA-inducible genes, but also revealed altered expression of genes involved in jasmonic acid (JA) responses, likely under the control of MYC2, a master switch in the JA signaling pathway. more...

Organism:: Arabidopsis thaliana

Type:: Expression profiling by array

Platform:: GPL198
4 Samples

Download data: CEL, TXT

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Accession:: GSE73841

ID:: 200073841

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000449222.

The purine metabolite allantoin enhances abiotic stress tolerance through synergistic activation of abscisic acid metabolism

(Submitter supplied) Purine catabolism is regarded as a housekeeping function that remobilizes nitrogen for plant growth and development. However, emerging evidence suggests that certain purine metabolites might contribute to stress protection of plants. Here, we show that in Arabidopsis, the intermediary metabolite allantoin plays a role in abiotic stress tolerance via activation of abscisic acid (ABA) metabolism. The aln loss-of-function of ALN, encoding allantoinase, results in increased allantoin accumulation, genome-wide up-regulation of stress-related genes, and enhanced tolerance to drought-shock and osmotic stress in aln mutant seedlings. more...